MII IG Kerndatensatz-Modul Biobank
2027.0.0-ballot - Germany

This page is part of the MII IG Kerndatensatz-Modul Biobank (v2027.0.0-ballot: 2027 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

: Organoid Lungenbiopsie

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<Specimen xmlns="http://hl7.org/fhir">
  <id value="OrganoidLunge"/>
  <meta>
    <profile
             value="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-pr-biobank-zellinie-organoid"/>
  </meta>
  <language value="en"/>
  <text>
    <status value="extensions"/>
    <div xml:lang="en" lang="en"><hr/><p><b>English</b></p><hr/><p class="res-header-id"><b>Generated Narrative: Specimen OrganoidLunge</b></p><a name="OrganoidLunge"> </a><a name="hcOrganoidLunge"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-mii-pr-biobank-zellinie-organoid.html">MII PR Biobank Specimen Zellinie Organoid</a></p></div><p><b>MII EX Biobank Kulturprotokoll</b>: <a href="DocumentReference-Kulturprotokoll.html">DocumentReference: status = current; date = 2018-06-20 09:00:00+0100; description = Standardprotokoll zur Kultivierung von Lungentumor-Organoiden</a></p><blockquote><p><b>MII EX Biobank Zelllinien-Modifikation</b></p><ul><li>artDerModifikation: <span title="Codes:{http://purl.obolibrary.org/obo/clo.owl CLO:0037375}">derives from cell with knockout gene</span></li><li>zielGen: <a href="http://terminology.hl7.org/6.3.0/CodeSystem-v3-hgnc.html#v3-hgnc-TP53">HUGO Gene Nomenclature Committee Genes: TP53</a> (tumor protein p53)</li><li>protokoll: <a href="DocumentReference-ProtocolCRISPRTP53.html">DocumentReference: status = current; date = 2018-06-19 09:00:00+0100; description = CRISPR Knockout-Protokoll für TP53 in Lungentumor-Organoiden</a></li></ul></blockquote><p><b>MII EX Biobank Anzahl Passagen</b>: 3</p><p><b>identifier</b>: <code>https://biobank.uk-musterstadt.de/fhir/sid/proben</code>/6789-ORG-1</p><p><b>status</b>: Available</p><p><b>type</b>: <span title="Codes:{http://snomed.info/sct 123038009}, {https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs Organoid}">Specimen (specimen)</span></p><p><b>subject</b>: <a href="https://simplifier.net/resolve?scope=de.basisprofil.r4@1.6.0&amp;canonical=http://fhir.org/packages/de.basisprofil.r4/Patient/mii-exa-test-data-patient-1">Patient/mii-exa-test-data-patient-1</a></p><p><b>parent</b>: </p><p><b style="color: maroon">Exception Generating Narrative: Cannot invoke &quot;org.hl7.fhir.r5.renderers.utils.ResourceWrapper.fhirType()&quot; because &quot;resource&quot; is null </b></p></div>
  </text>
  <extension
             url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-kulturprotokoll">
    <valueReference>🔗 
      <reference value="DocumentReference/Kulturprotokoll"/>
    </valueReference>
  </extension>
  <extension
             url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen">
    <extension url="artDerModifikation">
      <valueCodeableConcept>
        <coding>
          <system value="http://purl.obolibrary.org/obo/clo.owl"/>
          <code value="CLO:0037375"/>
          <display value="derives from cell with knockout gene"/>
        </coding>
      </valueCodeableConcept>
    </extension>
    <extension url="zielGen">
      <valueCoding>
        <system value="http://www.genenames.org"/>
        <code value="TP53"/>
        <display value="tumor protein p53"/>
      </valueCoding>
    </extension>
    <extension url="protokoll">
      <valueReference>🔗 
        <reference value="DocumentReference/ProtocolCRISPRTP53"/>
      </valueReference>
    </extension>
  </extension>
  <extension
             url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-passagen">
    <valueInteger value="3"/>
  </extension>
  <identifier>
    <system value="https://biobank.uk-musterstadt.de/fhir/sid/proben"/>
    <value value="6789-ORG-1"/>
  </identifier>
  <status value="available"/>
  <type>
    <coding>
      <system value="http://snomed.info/sct"/>
      <code value="123038009"/>
      <display value="Specimen (specimen)"/>
    </coding>
    <coding>
      <system
              value="https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs"/>
      <code value="Organoid"/>
      <display value="Organoids"/>
    </coding>
  </type>
  <subject>
    <reference value="Patient/mii-exa-test-data-patient-1"/>
  </subject>
  <parent>🔗 
    <reference value="Specimen/MusterprobeGewebe"/>
  </parent>
  <collection>
    <collectedDateTime value="2018-06-08T15:34:00+01:00"/>
  </collection>
  <processing>
    <extension
               url="https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen">
      <valueRange>
        <low>
          <value value="37"/>
          <unit value="°C"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="Cel"/>
        </low>
        <high>
          <value value="37"/>
          <unit value="°C"/>
          <system value="http://unitsofmeasure.org"/>
          <code value="Cel"/>
        </high>
      </valueRange>
    </extension>
    <procedure>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="1186936003"/>
        <display value="Storage of specimen (procedure)"/>
      </coding>
    </procedure>
    <timePeriod>
      <start value="2018-06-20T10:00:00+01:00"/>
      <end value="2018-06-27T10:00:00+01:00"/>
    </timePeriod>
  </processing>
  <container>
    <type>
      <coding>
        <system value="http://snomed.info/sct"/>
        <code value="83059008"/>
        <display value="Tube, device (physical object)"/>
      </coding>
    </type>
    <specimenQuantity>
      <value value="1"/>
      <unit value="ml"/>
      <system value="http://unitsofmeasure.org"/>
      <code value="ml"/>
    </specimenQuantity>
  </container>
</Specimen>