This page is part of the MII IG Kerndatensatz-Modul Biobank (v2027.0.0-ballot: 2027 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

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: MII VS Biobank Cellline Modification CLO

Active as of 2026-09-10

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{
  "resourceType" : "ValueSet",
  "id" : "mii-vs-biobank-cellline-modification-clo",
  "meta" : {
    "profile" : [
      🔗 "http://hl7.org/fhir/StructureDefinition/shareablevalueset"
    ]
  },
  "language" : "en",
  "text" : {
    "status" : "generated",
    "div" : "<div xml:lang=\"en\" lang=\"en\"><hr/><p><b>English</b></p><hr/><p class=\"res-header-id\"><b>Generated Narrative: ValueSet mii-vs-biobank-cellline-modification-clo</b></p><a name=\"mii-vs-biobank-cellline-modification-clo\"> </a><a name=\"hcmii-vs-biobank-cellline-modification-clo\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/uv/crmi/STU2/StructureDefinition-shareablevalueset.html\">Shareable ValueSet</a></p></div><ul><li>Include these codes as defined in <code>http://purl.obolibrary.org/obo/clo.owl</code><span title=\"Version is not explicitly stated. No matching Code System found\"> version Not Stated (use latest from terminology server)</span><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td>CLO:0037376</td><td>derived from cell with isogenic modification of gene</td></tr><tr><td>CLO:0037377</td><td>derived from cell with knockin gene</td></tr><tr><td>CLO:0037375</td><td>derives from cell with knockout gene</td></tr><tr><td>CLO:0037378</td><td>derived from cell with transgenic modification</td></tr></table></li></ul></div>"
  },
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      "valueCoding" : {
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        "code" : "semver",
        "display" : "SemVer"
      }
    },
    {
      "url" : "https://www.medizininformatik-initiative.de/fhir/modul-meta/StructureDefinition/mii-ex-meta-license-codeable",
      "valueCodeableConcept" : {
        "coding" : [
          {
            "system" : "http://hl7.org/fhir/spdx-license",
            "code" : "CC-BY-4.0",
            "display" : "Creative Commons Attribution 4.0 International"
          }
        ]
      }
    }
  ],
  "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/mii-vs-biobank-cellline-modification-clo",
  "version" : "2027.0.0-ballot",
  "name" : "MII_VS_Biobank_Cellline_Modification_CLO",
  "title" : "MII VS Biobank Cellline Modification CLO",
  "status" : "active",
  "experimental" : false,
  "date" : "2026-09-10",
  "publisher" : "Medizininformatik Initiative",
  "contact" : [
    {
      "name" : "Medizininformatik Initiative",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://www.medizininformatik-initiative.de/"
        }
      ]
    }
  ],
  "description" : "Value Set for Types of Cell Line Modifications (CLO)",
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "urn:iso:std:iso:3166",
          "code" : "DE",
          "display" : "Germany"
        }
      ]
    }
  ],
  "compose" : {
    "include" : [
      {
        "system" : "http://purl.obolibrary.org/obo/clo.owl",
        "concept" : [
          {
            "code" : "CLO:0037376",
            "display" : "derived from cell with isogenic modification of gene"
          },
          {
            "code" : "CLO:0037377",
            "display" : "derived from cell with knockin gene"
          },
          {
            "code" : "CLO:0037375",
            "display" : "derives from cell with knockout gene"
          },
          {
            "code" : "CLO:0037378",
            "display" : "derived from cell with transgenic modification"
          }
        ]
      }
    ]
  }
}