MII IG Kerndatensatz-Modul Molekulares Tumorboard
2027.0.0-ballot.1 - Germany

This page is part of the MII Implementation Guide Molecular Tumor Board (v2027.0.0-ballot.1: Release) based on FHIR (HL7® FHIR® Standard) R4. This is the current published version in its permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions

ValueSet: MII VS MTB Immunhistochemistry Specific Codes

Official URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/ValueSet/mii-vs-mtb-immunohistochemistry-specific-codes Version: 2027.0.0-ballot.1
Active as of 2026-09-15 Computable Name: MII_VS_MTB_Immunhistochemistry_Specific_Codes

Spezifische LOINC und SNOMED Codes für immunhistochemische Untersuchungen. Diese Codes werden für das Slice 'spezifisch' im Immunohistochemistry Profil verwendet.

References

This value set is not used here; it may be used elsewhere (e.g. specifications and/or implementations that use this content)

Logical Definition (CLD)

Language: de-DE

This value set includes codes based on the following rules:

  • Include codes fromhttp://snomed.info/sct version Not Stated (use latest from terminology server) where concept descends from 1234806008 (Observation using immunohistochemistry)
  • Include these codes as defined in http://loinc.org version Not Stated (use latest from terminology server)
    CodeDisplay
    55229-9 Immune stain study
    18474-7 HER2 Ag [Presence] in Tissue by Immune stain
    48676-1 HER2 Ag [Interpretation] in Tissue
    85319-2 HER2 [Presence] in Breast cancer specimen by Immune stain
    14228-1 Cells.estrogen receptor/cells in Tissue by Immune stain
    14230-7 Cells.progesterone receptor/cells in Tissue by Immune stain
    29593-1 Cells.Ki-67 nuclear Ag/cells in Tissue by Immune stain
    33055-5 Ki-67 nuclear Ag [Presence] in Tissue by Immune stain
    85330-9 Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain
    83052-1 PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain
    83055-4 PD-L1 by clone 28-8 [Presence] in Tissue by Immune stain
    83057-0 PD-L1 by clone SP142 [Presence] in Tissue by Immune stain
    81691-8 MLH-1 Ag [Presence] in Cancer specimen by Immune stain
    81692-6 MSH-2 Ag [Presence] in Cancer specimen by Immune stain
    81693-4 MSH-6 Ag [Presence] in Cancer specimen by Immune stain
    81694-2 PMS2 Ag [Presence] in Cancer specimen by Immune stain
    14229-9 P53 protein Ag [Presence] in Tissue by Immune stain
    47303-3 Anaplastic lymphoma kinase Ag [Presence] in Tissue by Immune stain
    47021-1 CDX2 Ag [Presence] in Tissue by Immune stain
    73910-2 PAX8 Ag [Presence] in Tissue by Immune stain
    48677-9 Cancer Ag 125 [Presence] in Tissue by Immune stain

 

Expansion

Expansion from 127.0.0.1 based on:

  • Loinc v2.83
  • SNOMED CT International edition 01-Jul 2025

This value set expansion contains 68 concepts.

SystemCodeDisplay (de-DE) - Deutsch (Deutschland) (German (Germany), de)JSONXML
http://snomed.info/sct  1236874005Intensity of stain of estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1237278006Intensity of stain of progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1255078008Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm by immunohistochemistry
http://snomed.info/sct  1255080002Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of adrenal gland by immunohistochemistry
http://snomed.info/sct  1255081003Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of appendix by immunohistochemistry
http://snomed.info/sct  1237281001Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1269169008Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of colon by immunohistochemistry
http://snomed.info/sct  1286760008Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of colorectum by immunohistochemistry
http://snomed.info/sct  1363519004Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of esophagus by immunohistochemistry
http://snomed.info/sct  1255079000Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of pancreas by immunohistochemistry
http://snomed.info/sct  1255082005Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of small intestine by immunohistochemistry
http://snomed.info/sct  1255076007Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of stomach by immunohistochemistry
http://snomed.info/sct  1279926000Percent of cell nuclei positive for proliferation marker protein Ki-67 in primary malignant neoplasm of thyroid by immunohistochemistry
http://snomed.info/sct  1234804006Percent of cells with estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1234803000Percent of cells with progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1255768001Presence of ALK tyrosine kinase receptor in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  1255615003Presence of anoctamin-1 in primary gastrointestinal stromal sarcoma by immunohistochemistry
http://snomed.info/sct  2040001000004100Presence of DNA mismatch repair protein Mlh1 in primary malignant neoplasm of colon by immunohistochemistry
http://snomed.info/sct  1286752007Presence of DNA mismatch repair protein Mlh1 in primary malignant neoplasm of colorectum by immunohistochemistry
http://snomed.info/sct  1255083000Presence of DNA mismatch repair protein Mlh1 in primary malignant neoplasm of endometrium by immunohistochemistry
http://snomed.info/sct  1255098003Presence of DNA mismatch repair protein Mlh1 in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  1255068005Presence of DNA mismatch repair protein Msh2 in primary malignant neoplasm of colon by immunohistochemistry
http://snomed.info/sct  1286764004Presence of DNA mismatch repair protein Msh2 in primary malignant neoplasm of colorectum by immunohistochemistry
http://snomed.info/sct  1255089001Presence of DNA mismatch repair protein Msh2 in primary malignant neoplasm of endometrium by immunohistochemistry
http://snomed.info/sct  1255099006Presence of DNA mismatch repair protein Msh2 in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  1255069002Presence of DNA mismatch repair protein Msh6 in primary malignant neoplasm of colon by immunohistochemistry
http://snomed.info/sct  1286763005Presence of DNA mismatch repair protein Msh6 in primary malignant neoplasm of colorectum by immunohistochemistry
http://snomed.info/sct  1255090005Presence of DNA mismatch repair protein Msh6 in primary malignant neoplasm of endometrium by immunohistochemistry
http://snomed.info/sct  1255100003Presence of DNA mismatch repair protein Msh6 in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  1234805007Presence of estrogen receptor in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1255093007Presence of estrogen receptor in primary malignant neoplasm of endometrium by immunohistochemistry
http://snomed.info/sct  1255614004Presence of mast/stem cell growth factor receptor Kit in primary gastrointestinal stromal sarcoma by immunohistochemistry
http://snomed.info/sct  1255070001Presence of mismatch repair endonuclease PMS2 in primary malignant neoplasm of colon by immunohistochemistry
http://snomed.info/sct  1286762000Presence of mismatch repair endonuclease PMS2 in primary malignant neoplasm of colorectum by immunohistochemistry
http://snomed.info/sct  1255091009Presence of mismatch repair endonuclease PMS2 in primary malignant neoplasm of endometrium by immunohistochemistry
http://snomed.info/sct  1255097008Presence of mismatch repair endonuclease PMS2 in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  1234801003Presence of progesterone receptor in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1255094001Presence of progesterone receptor in primary malignant neoplasm of endometrium by immunohistochemistry
http://snomed.info/sct  1255770005Presence of programmed cell death 1 ligand 1 in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  1255769009Presence of proto-oncogene tyrosine-protein kinase ROS in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  3550001000004108Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of breast by immunohistochemistry
http://snomed.info/sct  1255095000Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of endometrium by immunohistochemistry
http://snomed.info/sct  1255771009Presence of receptor tyrosine-protein kinase erbB-2 in primary malignant neoplasm of lung by immunohistochemistry
http://snomed.info/sct  1255616002Presence of succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial in primary gastrointestinal stromal sarcoma by immunohistochemistry
http://snomed.info/sct  1255617006Presence of succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial in primary gastrointestinal stromal sarcoma by immunohistochemistry
http://snomed.info/sct  4600001000004108Status of estrogen receptor stain in control cells by immunohistochemistry
http://snomed.info/sct  4050001000004108Status of progesterone receptor stain in control cells by immunohistochemistry
http://loinc.org  55229-9Immune stain study
http://loinc.org  18474-7HER2 Ag [Presence] in Tissue by Immune stain
http://loinc.org  48676-1HER2 Ag [Interpretation] in Tissue
http://loinc.org  85319-2HER2 [Presence] in Breast cancer specimen by Immune stain
http://loinc.org  14228-1Cells.estrogen receptor/cells in Tissue by Immune stain
http://loinc.org  14230-7Cells.progesterone receptor/cells in Tissue by Immune stain
http://loinc.org  29593-1Cells.Ki-67 nuclear Ag/cells in Tissue by Immune stain
http://loinc.org  33055-5Ki-67 nuclear Ag [Presence] in Tissue by Immune stain
http://loinc.org  85330-9Cells.Ki-67 nuclear Ag/cells in Breast cancer specimen by Immune stain
http://loinc.org  83052-1PD-L1 by clone 22C3 [Presence] in Tissue by Immune stain
http://loinc.org  83055-4PD-L1 by clone 28-8 [Presence] in Tissue by Immune stain
http://loinc.org  83057-0PD-L1 by clone SP142 [Presence] in Tissue by Immune stain
http://loinc.org  81691-8MLH-1 Ag [Presence] in Cancer specimen by Immune stain
http://loinc.org  81692-6MSH-2 Ag [Presence] in Cancer specimen by Immune stain
http://loinc.org  81693-4MSH-6 Ag [Presence] in Cancer specimen by Immune stain
http://loinc.org  81694-2PMS2 Ag [Presence] in Cancer specimen by Immune stain
http://loinc.org  14229-9P53 protein Ag [Presence] in Tissue by Immune stain
http://loinc.org  47303-3Anaplastic lymphoma kinase Ag [Presence] in Tissue by Immune stain
http://loinc.org  47021-1CDX2 Ag [Presence] in Tissue by Immune stain
http://loinc.org  73910-2PAX8 Ag [Presence] in Tissue by Immune stain
http://loinc.org  48677-9Cancer Ag 125 [Presence] in Tissue by Immune stain

Description of the above table(s).