MII EX Biobank Zelllinien-Modifikation - MII IG Kerndatensatz-Modul Biobank v2027.0.0-ballot

MII IG Kerndatensatz-Modul Biobank
2027.0.0-ballot - Germany

This page is part of the MII IG Kerndatensatz-Modul Biobank (v2027.0.0-ballot: 2027 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

Extension: MII EX Biobank Cell Line Modification

Official URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen				Version: 2027.0.0-ballot
Active as of 2026-09-11				Computable Name: MII_EX_Biobank_Modifikationen

Extension for describing modifications to cell lines, including type of modification, target gene, and reference to the protocol.

Context of Use

This extension may be used on the following element(s)

Element ID: Specimen

Usage info

Usages:

Use this Extension: MII PR Biobank Specimen Zellinie Organoid
Examples for this Extension: Specimen/OrganoidLunge

You can also check for usages in the FHIR IG Statistics

Formal Views of Extension Content

Description of Profiles, Differentials, Snapshots, and their representations.

Differential Table
Snapshot Table
Statistics/References
AllAll

Name	Flags	Card.	Type	Description & Constraints Filter: Bindings Constraints Obligations
Extension		0..*	Extension	MII EX Biobank Zelllinien-Modifikation
Slices for extension				Content/Rules for all slices
extension:artDerModifikation	S	0..1	Extension	Extension
extension		0..0		Extension
url		1..1	uri	"artDerModifikation"
value[x]		0..1	CodeableConcept	Value of extension Binding: MII VS Biobank Cellline Modification CLO (required)
extension:zielGen	S	0..1	Extension	Extension
extension		0..0		Extension
url		1..1	uri	"zielGen"
value[x]		0..1	Coding	Value of extension
system		0..1	uri	Identity of the terminology system Required Pattern: http://www.genenames.org
extension:protokoll	S	0..1	Extension	Extension
extension		0..0		Extension
url		1..1	uri	"protokoll"
value[x]		0..1	Reference(DocumentReference)	Value of extension
url		1..1	uri	"https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen"
value[x]		0..0		Value of extension
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
Extension.extension:artDerModifikation.value[x]	Base	required	MII VS Biobank Cellline Modification CLO	📦2027.0.0-ballot	This IG

Name	Flags	Card.	Type	Description & Constraints Filter: Bindings Constraints Obligations
Extension		0..*	Extension	MII EX Biobank Zelllinien-Modifikation
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
extension:artDerModifikation	S	0..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0		Extension Slice: Unordered, Open by value:url
url		1..1	uri	"artDerModifikation"
value[x]		0..1	CodeableConcept	Value of extension Binding: MII VS Biobank Cellline Modification CLO (required)
extension:zielGen	S	0..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0		Extension Slice: Unordered, Open by value:url
url		1..1	uri	"zielGen"
value[x]		0..1	Coding	Value of extension
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://www.genenames.org
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
extension:protokoll	S	0..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0		Extension Slice: Unordered, Open by value:url
url		1..1	uri	"protokoll"
value[x]		0..1	Reference(DocumentReference)	Value of extension
url		1..1	uri	"https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen"
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Extension.extension:artDerModifikation.value[x]	Base	required	MII VS Biobank Cellline Modification CLO	📦2027.0.0-ballot	This IG

Constraints

Id	Grade	Path(s)	Description	Expression
ele-1	error	ALL elements	All FHIR elements must have a @value or children	`hasValue() or (children().count() > id.count())`
ext-1	error	ALL extensions	Must have either extensions or value[x], not both	`extension.exists() != value.exists()`

Summary

Complex Extension: Erweiterung zur Beschreibung von Modifikationen an Zelllinien, einschließlich Art der Modifikation, Zielgen und Referenz zum Protokoll.

artDerModifikation: CodeableConcept: An Extension
zielGen: Coding: An Extension
protokoll: Reference: An Extension

Differential ViewDifferential View

Name	Flags	Card.	Type	Description & Constraints Filter: Bindings Constraints Obligations
Extension		0..*	Extension	MII EX Biobank Zelllinien-Modifikation
Slices for extension				Content/Rules for all slices
extension:artDerModifikation	S	0..1	Extension	Extension
extension		0..0		Extension
url		1..1	uri	"artDerModifikation"
value[x]		0..1	CodeableConcept	Value of extension Binding: MII VS Biobank Cellline Modification CLO (required)
extension:zielGen	S	0..1	Extension	Extension
extension		0..0		Extension
url		1..1	uri	"zielGen"
value[x]		0..1	Coding	Value of extension
system		0..1	uri	Identity of the terminology system Required Pattern: http://www.genenames.org
extension:protokoll	S	0..1	Extension	Extension
extension		0..0		Extension
url		1..1	uri	"protokoll"
value[x]		0..1	Reference(DocumentReference)	Value of extension
url		1..1	uri	"https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen"
value[x]		0..0		Value of extension
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
Extension.extension:artDerModifikation.value[x]	Base	required	MII VS Biobank Cellline Modification CLO	📦2027.0.0-ballot	This IG

Snapshot View

Name	Flags	Card.	Type	Description & Constraints Filter: Bindings Constraints Obligations
Extension		0..*	Extension	MII EX Biobank Zelllinien-Modifikation
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
extension:artDerModifikation	S	0..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0		Extension Slice: Unordered, Open by value:url
url		1..1	uri	"artDerModifikation"
value[x]		0..1	CodeableConcept	Value of extension Binding: MII VS Biobank Cellline Modification CLO (required)
extension:zielGen	S	0..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0		Extension Slice: Unordered, Open by value:url
url		1..1	uri	"zielGen"
value[x]		0..1	Coding	Value of extension
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://www.genenames.org
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
extension:protokoll	S	0..1	Extension	Extension
id		0..1	string	Unique id for inter-element referencing
extension		0..0		Extension Slice: Unordered, Open by value:url
url		1..1	uri	"protokoll"
value[x]		0..1	Reference(DocumentReference)	Value of extension
url		1..1	uri	"https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen"
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Extension.extension:artDerModifikation.value[x]	Base	required	MII VS Biobank Cellline Modification CLO	📦2027.0.0-ballot	This IG

Constraints

Id	Grade	Path(s)	Description	Expression
ele-1	error	ALL elements	All FHIR elements must have a @value or children	`hasValue() or (children().count() > id.count())`
ext-1	error	ALL extensions	Must have either extensions or value[x], not both	`extension.exists() != value.exists()`

Summary

Complex Extension: Erweiterung zur Beschreibung von Modifikationen an Zelllinien, einschließlich Art der Modifikation, Zielgen und Referenz zum Protokoll.

artDerModifikation: CodeableConcept: An Extension
zielGen: Coding: An Extension
protokoll: Reference: An Extension

Other representations of profile: CSV, Excel, Schematron

IG © 2021+ Medizininformatik Initiative. Package de.medizininformatikinitiative.kerndatensatz.biobank#2027.0.0-ballot based on FHIR 4.0.1. Generated 2026-09-11
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