MII IG Kerndatensatz-Modul Biobank
2027.0.0-ballot - Germany

This page is part of the MII IG Kerndatensatz-Modul Biobank (v2027.0.0-ballot: 2027 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

: Organoid Lungenbiopsie

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{
  "resourceType" : "Specimen",
  "id" : "OrganoidLunge",
  "meta" : {
    "profile" : [
      🔗 "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-pr-biobank-zellinie-organoid"
    ]
  },
  "language" : "de",
  "text" : {
    "status" : "extensions",
    "div" : "<div xml:lang=\"de\" lang=\"de\"><hr/><p><b>German</b></p><hr/><p class=\"res-header-id\"><b>Generated Narrative: Specimen OrganoidLunge</b></p><a name=\"de-OrganoidLunge\"> </a><a name=\"de-hcOrganoidLunge\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-mii-pr-biobank-zellinie-organoid.html\">MII PR Biobank Specimen Zellinie Organoid</a></p></div><p><b>MII EX Biobank Kulturprotokoll</b>: <a href=\"DocumentReference-Kulturprotokoll.html\">DocumentReference: status = current; date = 2018-06-20 09:00:00+0100; description = Standardprotokoll zur Kultivierung von Lungentumor-Organoiden</a></p><blockquote><p><b>MII EX Biobank Zelllinien-Modifikation</b></p><ul><li>artDerModifikation: <span title=\"Codes:{http://purl.obolibrary.org/obo/clo.owl CLO:0037375}\">derives from cell with knockout gene</span></li><li>zielGen: <a href=\"http://terminology.hl7.org/6.3.0/CodeSystem-v3-hgnc.html#v3-hgnc-TP53\">HUGO Gene Nomenclature Committee Genes: TP53</a> (tumor protein p53)</li><li>protokoll: <a href=\"DocumentReference-ProtocolCRISPRTP53.html\">DocumentReference: status = current; date = 2018-06-19 09:00:00+0100; description = CRISPR Knockout-Protokoll für TP53 in Lungentumor-Organoiden</a></li></ul></blockquote><p><b>MII EX Biobank Anzahl Passagen</b>: 3</p><p><b>identifier</b>: <code>https://biobank.uk-musterstadt.de/fhir/sid/proben</code>/6789-ORG-1</p><p><b>status</b>: Available</p><p><b>type</b>: <span title=\"Codes:{http://snomed.info/sct 123038009}, {https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs Organoid}\">Specimen (specimen)</span></p><p><b>subject</b>: <a href=\"https://simplifier.net/resolve?scope=de.basisprofil.r4@1.6.0&amp;canonical=http://fhir.org/packages/de.basisprofil.r4/Patient/mii-exa-test-data-patient-1\">Patient/mii-exa-test-data-patient-1</a></p><p><b>parent</b>: </p><p><b style=\"color: maroon\">Exception Generating Narrative: Cannot invoke &quot;org.hl7.fhir.r5.renderers.utils.ResourceWrapper.fhirType()&quot; because &quot;resource&quot; is null </b></p></div>"
  },
  "extension" : [
    {
      "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-kulturprotokoll",
      "valueReference" : {
        🔗 "reference" : "DocumentReference/Kulturprotokoll"
      }
    },
    {
      "extension" : [
        {
          "url" : "artDerModifikation",
          "valueCodeableConcept" : {
            "coding" : [
              {
                "system" : "http://purl.obolibrary.org/obo/clo.owl",
                "code" : "CLO:0037375",
                "display" : "derives from cell with knockout gene"
              }
            ]
          }
        },
        {
          "url" : "zielGen",
          "valueCoding" : {
            "system" : "http://www.genenames.org",
            "code" : "TP53",
            "display" : "tumor protein p53"
          }
        },
        {
          "url" : "protokoll",
          "valueReference" : {
            🔗 "reference" : "DocumentReference/ProtocolCRISPRTP53"
          }
        }
      ],
      "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-modifikationen"
    },
    {
      "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-passagen",
      "valueInteger" : 3
    }
  ],
  "identifier" : [
    {
      "system" : "https://biobank.uk-musterstadt.de/fhir/sid/proben",
      "value" : "6789-ORG-1"
    }
  ],
  "status" : "available",
  "type" : {
    "coding" : [
      {
        "system" : "http://snomed.info/sct",
        "code" : "123038009",
        "display" : "Specimen (specimen)"
      },
      {
        "system" : "https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs",
        "code" : "Organoid",
        "display" : "Organoids"
      }
    ]
  },
  "subject" : {
    "reference" : "Patient/mii-exa-test-data-patient-1"
  },
  "parent" : [
    {
      🔗 "reference" : "Specimen/MusterprobeGewebe"
    }
  ],
  "collection" : {
    "collectedDateTime" : "2018-06-08T15:34:00+01:00"
  },
  "processing" : [
    {
      "extension" : [
        {
          "url" : "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen",
          "valueRange" : {
            "low" : {
              "value" : 37,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            },
            "high" : {
              "value" : 37,
              "unit" : "°C",
              "system" : "http://unitsofmeasure.org",
              "code" : "Cel"
            }
          }
        }
      ],
      "procedure" : {
        "coding" : [
          {
            "system" : "http://snomed.info/sct",
            "code" : "1186936003",
            "display" : "Storage of specimen (procedure)"
          }
        ]
      },
      "timePeriod" : {
        "start" : "2018-06-20T10:00:00+01:00",
        "end" : "2018-06-27T10:00:00+01:00"
      }
    }
  ],
  "container" : [
    {
      "type" : {
        "coding" : [
          {
            "system" : "http://snomed.info/sct",
            "code" : "83059008",
            "display" : "Tube, device (physical object)"
          }
        ]
      },
      "specimenQuantity" : {
        "value" : 1,
        "unit" : "ml",
        "system" : "http://unitsofmeasure.org",
        "code" : "ml"
      }
    }
  ]
}