This page is part of the MII IG Kerndatensatz-Modul Biobank (v2027.0.0-ballot: 2027 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

• Inhalt
• Detaillierte Beschreibungen
• Mappings
• Beispiele
• XML
• JSON

Ressourcenprofil: MII PR Biobank Specimen Bioprobe

Abbildung einer MII Bioprobe

Usages:

• Derived from this Profile: MII PR Biobank Specimen Zellinie Organoid
• Examples for this Profile: Specimen/AliquotBuffyCoat1, Specimen/AliquotBuffyCoat2, Specimen/AliquotgruppeBuffyCoat, Specimen/AliquotgruppeDNA... Show 3 more, Specimen/AliquotgruppePlasma, Specimen/MusterprobeFluessig and Specimen/MusterprobeGewebe
• CapabilityStatements using this Profile: MII CPS Biobank CapabilityStatement

You can also check for usages in the FHIR IG Statistics

Formale Ansichten des Profilinhalts

Beschreibung von Profilen, Differentials, Snapshots und deren Repräsentationen.

• Schlüsselelemente-Tabelle
• Differential-Tabelle
• Snapshot-Tabelle
• Statistiken/Referenzen
• Alle

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	MII_PR_Biobank_Specimen_Bioprobe_Core	Sample for analysis
id	SΣ	0..1	id	Logical id of this artifact
meta	SΣ	0..1	Meta	Metadata about the resource
source	SΣ	0..1	uri	Identifies where the resource comes from
profile	SΣ	0..*	canonical(StructureDefinition)	Profiles this resource claims to conform to
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension				Content/Rules for all slices
extension:feature		0..*	(Complex)	MII EX Biobank Feature R5 URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Specimen.feature
extension:probenebene	S	0..*	Coding	MII EX Biobank Ebene URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-ebene Binding: MII VS Biobank Probenebene (required)
extension:infektiositaetsstatus	S	0..1	CodeableConcept	MII EX Biobank Infektiositätsstatus URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-infektiositaetsstatus Binding: MII VS Biobank Biosafety-Level Einstufung [SNOMED CT] (required)
extension:focus	S	0..1	Reference(RelatedPerson | Group | Device | Substance | Location)	Specimen Focus URL: http://hl7.eu/fhir/laboratory/StructureDefinition/specimen-focus
extension:festgestellteDiagnose	S	0..1	Reference(Condition)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
extension:gehoertZu	S	0..1	Reference(MII PR Biobank Organization Sammlung Biobank)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
extension:anzahlAliquots	S	0..1	integer	MII EX Biobank Anzahl Aliquots URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	0..*	Identifier
status	?!SΣ	1..1	code	Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	1..1	CodeableConcept	Binding: hl7VS-specimenType (example): The type of the specimen.
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Probenart SCT (extensible)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
coding:miabis-type	SΣ	0..1	Coding	Code defined by a terminology system Binding: DetailedSampleTypeVS (required)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs
subject	SΣ	1..1	Reference(Patient)
receivedTime	SΣ	0..1	dateTime	The time when specimen was received for processing
parent	S	0..*	Reference(Specimen)
request	S	0..*	Reference(ServiceRequest)
collection	S	1..1	BackboneElement
Slices for extension				Content/Rules for all slices
extension:einstellungBlutversorgung	S	0..1	dateTime	MII EX Biobank Einstellung Blutversorgung URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/EinstellungBlutversorgung
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collected[x]	SΣ	1..1
collectedDateTime			dateTime
collectedPeriod			Period
quantity	S	0..1	SimpleQuantity(4.0.1)
Slices for extension				Content/Rules for all slices
extension:pqTranslation		0..*	Quantity	Same quantity with different units URL: http://hl7.org/fhir/StructureDefinition/iso21090-PQ-translation
extension:quantityPrecision		0..1	integer	Explicit precision (number of significant decimal places) URL: http://hl7.org/fhir/StructureDefinition/quantity-precision
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
method	S	0..1	CodeableConcept	Technique used to perform collection Binding: FHIRSpecimenCollectionMethod (example): The technique that is used to perform the procedure.
coding	SΣ	0..*	Coding	Code defined by a terminology system
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
bodySite	SC	0..1	CodeableConcept	Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality. Constraints: mii-bb-1
Slices for coding	Σ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:sct	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Biobank BodyStructures SCT (required)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
coding:icd-o-3	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Onkologie ICD-O-3 Topographie (required)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://terminology.hl7.org/CodeSystem/icd-o-3
Slices for fastingStatus[x]	SΣ	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-relevantClincialInformation (extensible): Codes describing the fasting status of the patient.
fastingStatusCodeableConcept			CodeableConcept
fastingStatusDuration			Duration
fastingStatus[x]:fastingStatusCodeableConcept	Σ	0..1	CodeableConcept	Whether or how long patient abstained from food and/or drink Binding: hl7VS-relevantClincialInformation (required)
coding	Σ	0..*	Coding	Code defined by a terminology system
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
Slices for processing	S	0..*	BackboneElement	Slice: Unordered, Open by value:$this.procedure
processing:All Slices				Content/Rules for all slices
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
extension:temperature-miabis	S	0..1	CodeableConcept	Sample storage temperature URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension Binding: Storage Temperature Value Set (required)
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
procedure	S	1..1	CodeableConcept	Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen.
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Laboratory Procedure SCT (preferred)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
additive	S	0..*	Reference(MII PR Biobank Substance Additiv)
Slices for time[x]	S	0..1		Date and time of specimen processing Slice: Unordered, Open by type:$this
timeDateTime			dateTime
timePeriod			Period
time[x]:timePeriod	S	0..1	Period
start	SΣC	0..1	dateTime	Starting time with inclusive boundary
end	SΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
processing:lagerprozess	S	0..*	BackboneElement	Processing and processing step details
Slices for extension	S	1..*	Extension	Extension Slice: Unordered, Open by value:url
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
procedure		1..1	CodeableConcept	Indicates the treatment step applied to the specimen Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 1186936003
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
Slices for time[x]		1..1	Period	Date and time of specimen processing Slice: Unordered, Closed by type:$this
Slices for time[x]				Content/Rules for all slices
time[x]:timePeriod		1..1	Period	Date and time of specimen processing
start	ΣC	1..1	dateTime	Starting time with inclusive boundary
container	S	1..*	BackboneElement
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	S	1..1	CodeableConcept	Binding: MII VS Biobank Containertyp SCT (extensible)
coding	SΣ	1..*	Coding	Code defined by a terminology system
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
capacity	S	0..1	SimpleQuantity(4.0.1)
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
specimenQuantity	S	0..1	SimpleQuantity(4.0.1)
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
Slices for additive[x]	S	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-additivePreservative (example): Substance added to specimen container.
additiveCodeableConcept			CodeableConcept
additiveReference			Reference(Substance)
additive[x]:additiveReference		0..1	Reference(MII PR Biobank Substance Additiv)	Additive associated with container
note	S	0..*	Annotation
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	hl7VS-specimenType	📦3.0.0	THO v7.2
Specimen.type.coding:sct	Base	extensible	MII VS Biobank Probenart SCT	📦2027.0.0-ballot	This IG
Specimen.type.coding:miabis-type	Base	required	DetailedSampleTypeVS	📦1.3.0	MIABIS on FHIR Implementation Guide v1.3
Specimen.collection.​method	Base	example	FHIR Specimen Collection Method	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite	Base	example	SNOMED CT Body Structures	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite.coding:sct	Base	required	MII VS Biobank BodyStructures SCT	📦2027.0.0-ballot	This IG
Specimen.collection.​bodySite.coding:icd-o-3	Base	required	MII VS Onkologie ICD-O-3 Topographie	⏿2025.1.0	127.0.0.1
Specimen.collection.​fastingStatus[x]	Base	extensible	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.collection.​fastingStatus[x]:fastingStatusCodeableConcept	Base	required	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.processing.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.processing.​procedure.coding:sct	Base	preferred	MII VS Biobank Laboratory Procedure SCT	📦2027.0.0-ballot	This IG
Specimen.processing:lagerprozess.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.container.type	Base	extensible	MII VS Biobank Containertyp SCT	📦2027.0.0-ballot	This IG
Specimen.container.additive[x]	Base	example	hl7VS-additivePreservative	📦3.0.0	THO v7.2

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
mii-bb-1	error	Specimen.collection.bodySite	Bei der Angabe der Entnahmestelle muss ein ICD-O-3 Topographiecode oder ein SNOMED CT Code angegeben werden.	coding.where(system = 'http://snomed.info/sct' or system = 'http://terminology.hl7.org/CodeSystem/icd-o-3').exists()

Diese Struktur ist abgeleitet von MII_PR_Biobank_Specimen_Bioprobe_Core

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	MII_PR_Biobank_Specimen_Bioprobe_Core	Sample for analysis
Slices for extension				Content/Rules for all slices
extension:festgestellteDiagnose	S	0..1	Reference(Condition)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
extension:gehoertZu	S	0..1	Reference(MII PR Biobank Organization Sammlung Biobank)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
extension:anzahlAliquots	S	0..1	integer	MII EX Biobank Anzahl Aliquots URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
type
Slices for coding				Content/Rules for all slices
coding:miabis-type	S	0..1	Coding	Code defined by a terminology system Binding: DetailedSampleTypeVS (required)
system		0..1	uri	Identity of the terminology system Required Pattern: https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs
collection
method	S	0..1	CodeableConcept	Technique used to perform collection
coding	S	0..*	Coding	Code defined by a terminology system
system	S	1..1	uri	Identity of the terminology system
code	S	1..1	code	Symbol in syntax defined by the system
processing		0..*	BackboneElement
extension		1..*	Extension	Extension
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen		1..1	MII_EX_Biobank_Temperaturbedingungen	MII EX Biobank Temperaturbedingungen
extension:temperature-miabis	S	0..1	CodeableConcept	Sample storage temperature URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension Binding: Storage Temperature Value Set (required)
Slices for processing				Content/Rules for all slices
processing:lagerprozess		0..*	BackboneElement	Processing and processing step details
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen		1..1	MII_EX_Biobank_Temperaturbedingungen	MII EX Biobank Temperaturbedingungen
container		1..*	BackboneElement
type
coding	S	1..*	Coding	Code defined by a terminology system
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
Specimen.type.coding:miabis-type	Base	required	DetailedSampleTypeVS	📦1.3.0	MIABIS on FHIR Implementation Guide v1.3

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	MII_PR_Biobank_Specimen_Bioprobe_Core	Sample for analysis
id	SΣ	0..1	id	Logical id of this artifact
meta	SΣ	0..1	Meta	Metadata about the resource
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
versionId	Σ	0..1	id	Version specific identifier
lastUpdated	Σ	0..1	instant	When the resource version last changed
source	SΣ	0..1	uri	Identifies where the resource comes from
profile	SΣ	0..*	canonical(StructureDefinition)	Profiles this resource claims to conform to
security	Σ	0..*	Coding	Security Labels applied to this resource Binding: All Security Labels (extensible): Security Labels from the Healthcare Privacy and Security Classification System.
tag	Σ	0..*	Coding	Tags applied to this resource Binding: CommonTags (example): Codes that represent various types of tags, commonly workflow-related; e.g. "Needs review by Dr. Jones".
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:feature		0..*	(Complex)	MII EX Biobank Feature R5 URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Specimen.feature
extension:probenebene	S	0..*	Coding	MII EX Biobank Ebene URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-ebene Binding: MII VS Biobank Probenebene (required)
extension:infektiositaetsstatus	S	0..1	CodeableConcept	MII EX Biobank Infektiositätsstatus URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-infektiositaetsstatus Binding: MII VS Biobank Biosafety-Level Einstufung [SNOMED CT] (required)
extension:focus	S	0..1	Reference(RelatedPerson | Group | Device | Substance | Location)	Specimen Focus URL: http://hl7.eu/fhir/laboratory/StructureDefinition/specimen-focus
extension:festgestellteDiagnose	S	0..1	Reference(Condition)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
extension:gehoertZu	S	0..1	Reference(MII PR Biobank Organization Sammlung Biobank)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
extension:anzahlAliquots	S	0..1	integer	MII EX Biobank Anzahl Aliquots URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	0..*	Identifier
accessionIdentifier	Σ	0..1	Identifier	Identifier assigned by the lab
status	?!SΣ	1..1	code	Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	1..1	CodeableConcept	Binding: hl7VS-specimenType (example): The type of the specimen.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Probenart SCT (extensible)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:miabis-type	SΣ	0..1	Coding	Code defined by a terminology system Binding: DetailedSampleTypeVS (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(Patient)
receivedTime	SΣ	0..1	dateTime	The time when specimen was received for processing
parent	S	0..*	Reference(Specimen)
request	S	0..*	Reference(ServiceRequest)
collection	S	1..1	BackboneElement
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:einstellungBlutversorgung	S	0..1	dateTime	MII EX Biobank Einstellung Blutversorgung URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/EinstellungBlutversorgung
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collector	Σ	0..1	Reference(Practitioner | PractitionerRole)	Who collected the specimen
collected[x]	SΣ	1..1
collectedDateTime			dateTime
collectedPeriod			Period
duration	Σ	0..1	Duration	How long it took to collect specimen
quantity	S	0..1	SimpleQuantity(4.0.1)
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
extension:pqTranslation		0..*	Quantity	Same quantity with different units URL: http://hl7.org/fhir/StructureDefinition/iso21090-PQ-translation
extension:quantityPrecision		0..1	integer	Explicit precision (number of significant decimal places) URL: http://hl7.org/fhir/StructureDefinition/quantity-precision
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
method	S	0..1	CodeableConcept	Technique used to perform collection Binding: FHIRSpecimenCollectionMethod (example): The technique that is used to perform the procedure.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	SΣ	0..*	Coding	Code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
bodySite	SC	0..1	CodeableConcept	Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality. Constraints: mii-bb-1
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	Σ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:sct	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Biobank BodyStructures SCT (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:icd-o-3	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Onkologie ICD-O-3 Topographie (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://terminology.hl7.org/CodeSystem/icd-o-3
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
Slices for fastingStatus[x]	SΣ	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-relevantClincialInformation (extensible): Codes describing the fasting status of the patient.
fastingStatusCodeableConcept			CodeableConcept
fastingStatusDuration			Duration
fastingStatus[x]:fastingStatusCodeableConcept	Σ	0..1	CodeableConcept	Whether or how long patient abstained from food and/or drink Binding: hl7VS-relevantClincialInformation (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	Σ	0..*	Coding	Code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
Slices for processing	S	0..*	BackboneElement	Slice: Unordered, Open by value:$this.procedure
processing:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
extension:temperature-miabis	S	0..1	CodeableConcept	Sample storage temperature URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension Binding: Storage Temperature Value Set (required)
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
description		0..1	string	Textual description of procedure
procedure	S	1..1	CodeableConcept	Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Laboratory Procedure SCT (preferred)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
additive	S	0..*	Reference(MII PR Biobank Substance Additiv)
Slices for time[x]	S	0..1		Date and time of specimen processing Slice: Unordered, Open by type:$this
timeDateTime			dateTime
timePeriod			Period
time[x]:timePeriod	S	0..1	Period
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	0..1	dateTime	Starting time with inclusive boundary
end	SΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
processing:lagerprozess	S	0..*	BackboneElement	Processing and processing step details
id		0..1	string	Unique id for inter-element referencing
Slices for extension	S	1..*	Extension	Extension Slice: Unordered, Open by value:url
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
description		0..1	string	Textual description of procedure
procedure		1..1	CodeableConcept	Indicates the treatment step applied to the specimen Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 1186936003
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
additive		0..*	Reference(Substance)	Material used in the processing step
Slices for time[x]		1..1	Period	Date and time of specimen processing Slice: Unordered, Closed by type:$this
Slices for time[x]				Content/Rules for all slices
time[x]:timePeriod		1..1	Period	Date and time of specimen processing
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	ΣC	1..1	dateTime	Starting time with inclusive boundary
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
container	S	1..*	BackboneElement
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
identifier	Σ	0..*	Identifier	Id for the container
description		0..1	string	Textual description of the container
type	S	1..1	CodeableConcept	Binding: MII VS Biobank Containertyp SCT (extensible)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	SΣ	1..*	Coding	Code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
capacity	S	0..1	SimpleQuantity(4.0.1)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
specimenQuantity	S	0..1	SimpleQuantity(4.0.1)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
Slices for additive[x]	S	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-additivePreservative (example): Substance added to specimen container.
additiveCodeableConcept			CodeableConcept
additiveReference			Reference(Substance)
additive[x]:additiveReference		0..1	Reference(MII PR Biobank Substance Additiv)	Additive associated with container
condition	Σ	0..*	CodeableConcept	State of the specimen Binding: hl7VS-specimenCondition (extensible): Codes describing the state of the specimen.
note	S	0..*	Annotation
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.meta.security	Base	extensible	SecurityLabels	📍4.0.1	FHIR Std.
Specimen.meta.tag	Base	example	Common Tags	📍4.0.1	FHIR Std.
Specimen.language	Base	preferred	Common Languages	📍4.0.1	FHIR Std.
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	hl7VS-specimenType	📦3.0.0	THO v7.2
Specimen.type.coding:sct	Base	extensible	MII VS Biobank Probenart SCT	📦2027.0.0-ballot	This IG
Specimen.type.coding:miabis-type	Base	required	DetailedSampleTypeVS	📦1.3.0	MIABIS on FHIR Implementation Guide v1.3
Specimen.collection.​method	Base	example	FHIR Specimen Collection Method	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite	Base	example	SNOMED CT Body Structures	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite.coding:sct	Base	required	MII VS Biobank BodyStructures SCT	📦2027.0.0-ballot	This IG
Specimen.collection.​bodySite.coding:icd-o-3	Base	required	MII VS Onkologie ICD-O-3 Topographie	⏿2025.1.0	127.0.0.1
Specimen.collection.​fastingStatus[x]	Base	extensible	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.collection.​fastingStatus[x]:fastingStatusCodeableConcept	Base	required	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.processing.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.processing.​procedure.coding:sct	Base	preferred	MII VS Biobank Laboratory Procedure SCT	📦2027.0.0-ballot	This IG
Specimen.processing:lagerprozess.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.container.type	Base	extensible	MII VS Biobank Containertyp SCT	📦2027.0.0-ballot	This IG
Specimen.container.additive[x]	Base	example	hl7VS-additivePreservative	📦3.0.0	THO v7.2
Specimen.condition	Base	extensible	hl7VS-specimenCondition	📦3.0.0	THO v7.2

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
mii-bb-1	error	Specimen.collection.bodySite	Bei der Angabe der Entnahmestelle muss ein ICD-O-3 Topographiecode oder ein SNOMED CT Code angegeben werden.	coding.where(system = 'http://snomed.info/sct' or system = 'http://terminology.hl7.org/CodeSystem/icd-o-3').exists()

Diese Struktur ist abgeleitet von MII_PR_Biobank_Specimen_Bioprobe_Core

Summary

Mandatory: 2 elements(5 nested mandatory elements)
Must-Support: 10 elements

Extensions

This structure refers to these extensions:

• https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
• https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
• https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension

Schlüsselelemente-Ansicht

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	MII_PR_Biobank_Specimen_Bioprobe_Core	Sample for analysis
id	SΣ	0..1	id	Logical id of this artifact
meta	SΣ	0..1	Meta	Metadata about the resource
source	SΣ	0..1	uri	Identifies where the resource comes from
profile	SΣ	0..*	canonical(StructureDefinition)	Profiles this resource claims to conform to
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
Slices for extension				Content/Rules for all slices
extension:feature		0..*	(Complex)	MII EX Biobank Feature R5 URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Specimen.feature
extension:probenebene	S	0..*	Coding	MII EX Biobank Ebene URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-ebene Binding: MII VS Biobank Probenebene (required)
extension:infektiositaetsstatus	S	0..1	CodeableConcept	MII EX Biobank Infektiositätsstatus URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-infektiositaetsstatus Binding: MII VS Biobank Biosafety-Level Einstufung [SNOMED CT] (required)
extension:focus	S	0..1	Reference(RelatedPerson | Group | Device | Substance | Location)	Specimen Focus URL: http://hl7.eu/fhir/laboratory/StructureDefinition/specimen-focus
extension:festgestellteDiagnose	S	0..1	Reference(Condition)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
extension:gehoertZu	S	0..1	Reference(MII PR Biobank Organization Sammlung Biobank)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
extension:anzahlAliquots	S	0..1	integer	MII EX Biobank Anzahl Aliquots URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	0..*	Identifier
status	?!SΣ	1..1	code	Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	1..1	CodeableConcept	Binding: hl7VS-specimenType (example): The type of the specimen.
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Probenart SCT (extensible)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
coding:miabis-type	SΣ	0..1	Coding	Code defined by a terminology system Binding: DetailedSampleTypeVS (required)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs
subject	SΣ	1..1	Reference(Patient)
receivedTime	SΣ	0..1	dateTime	The time when specimen was received for processing
parent	S	0..*	Reference(Specimen)
request	S	0..*	Reference(ServiceRequest)
collection	S	1..1	BackboneElement
Slices for extension				Content/Rules for all slices
extension:einstellungBlutversorgung	S	0..1	dateTime	MII EX Biobank Einstellung Blutversorgung URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/EinstellungBlutversorgung
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collected[x]	SΣ	1..1
collectedDateTime			dateTime
collectedPeriod			Period
quantity	S	0..1	SimpleQuantity(4.0.1)
Slices for extension				Content/Rules for all slices
extension:pqTranslation		0..*	Quantity	Same quantity with different units URL: http://hl7.org/fhir/StructureDefinition/iso21090-PQ-translation
extension:quantityPrecision		0..1	integer	Explicit precision (number of significant decimal places) URL: http://hl7.org/fhir/StructureDefinition/quantity-precision
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
method	S	0..1	CodeableConcept	Technique used to perform collection Binding: FHIRSpecimenCollectionMethod (example): The technique that is used to perform the procedure.
coding	SΣ	0..*	Coding	Code defined by a terminology system
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
bodySite	SC	0..1	CodeableConcept	Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality. Constraints: mii-bb-1
Slices for coding	Σ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:sct	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Biobank BodyStructures SCT (required)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
coding:icd-o-3	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Onkologie ICD-O-3 Topographie (required)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://terminology.hl7.org/CodeSystem/icd-o-3
Slices for fastingStatus[x]	SΣ	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-relevantClincialInformation (extensible): Codes describing the fasting status of the patient.
fastingStatusCodeableConcept			CodeableConcept
fastingStatusDuration			Duration
fastingStatus[x]:fastingStatusCodeableConcept	Σ	0..1	CodeableConcept	Whether or how long patient abstained from food and/or drink Binding: hl7VS-relevantClincialInformation (required)
coding	Σ	0..*	Coding	Code defined by a terminology system
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
Slices for processing	S	0..*	BackboneElement	Slice: Unordered, Open by value:$this.procedure
processing:All Slices				Content/Rules for all slices
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
extension:temperature-miabis	S	0..1	CodeableConcept	Sample storage temperature URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension Binding: Storage Temperature Value Set (required)
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
procedure	S	1..1	CodeableConcept	Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen.
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Laboratory Procedure SCT (preferred)
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
additive	S	0..*	Reference(MII PR Biobank Substance Additiv)
Slices for time[x]	S	0..1		Date and time of specimen processing Slice: Unordered, Open by type:$this
timeDateTime			dateTime
timePeriod			Period
time[x]:timePeriod	S	0..1	Period
start	SΣC	0..1	dateTime	Starting time with inclusive boundary
end	SΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
processing:lagerprozess	S	0..*	BackboneElement	Processing and processing step details
Slices for extension	S	1..*	Extension	Extension Slice: Unordered, Open by value:url
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
procedure		1..1	CodeableConcept	Indicates the treatment step applied to the specimen Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 1186936003
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
Slices for time[x]		1..1	Period	Date and time of specimen processing Slice: Unordered, Closed by type:$this
Slices for time[x]				Content/Rules for all slices
time[x]:timePeriod		1..1	Period	Date and time of specimen processing
start	ΣC	1..1	dateTime	Starting time with inclusive boundary
container	S	1..*	BackboneElement
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	S	1..1	CodeableConcept	Binding: MII VS Biobank Containertyp SCT (extensible)
coding	SΣ	1..*	Coding	Code defined by a terminology system
system	SΣ	1..1	uri	Identity of the terminology system
code	SΣ	1..1	code	Symbol in syntax defined by the system
capacity	S	0..1	SimpleQuantity(4.0.1)
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
specimenQuantity	S	0..1	SimpleQuantity(4.0.1)
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
Slices for additive[x]	S	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-additivePreservative (example): Substance added to specimen container.
additiveCodeableConcept			CodeableConcept
additiveReference			Reference(Substance)
additive[x]:additiveReference		0..1	Reference(MII PR Biobank Substance Additiv)	Additive associated with container
note	S	0..*	Annotation
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	hl7VS-specimenType	📦3.0.0	THO v7.2
Specimen.type.coding:sct	Base	extensible	MII VS Biobank Probenart SCT	📦2027.0.0-ballot	This IG
Specimen.type.coding:miabis-type	Base	required	DetailedSampleTypeVS	📦1.3.0	MIABIS on FHIR Implementation Guide v1.3
Specimen.collection.​method	Base	example	FHIR Specimen Collection Method	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite	Base	example	SNOMED CT Body Structures	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite.coding:sct	Base	required	MII VS Biobank BodyStructures SCT	📦2027.0.0-ballot	This IG
Specimen.collection.​bodySite.coding:icd-o-3	Base	required	MII VS Onkologie ICD-O-3 Topographie	⏿2025.1.0	127.0.0.1
Specimen.collection.​fastingStatus[x]	Base	extensible	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.collection.​fastingStatus[x]:fastingStatusCodeableConcept	Base	required	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.processing.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.processing.​procedure.coding:sct	Base	preferred	MII VS Biobank Laboratory Procedure SCT	📦2027.0.0-ballot	This IG
Specimen.processing:lagerprozess.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.container.type	Base	extensible	MII VS Biobank Containertyp SCT	📦2027.0.0-ballot	This IG
Specimen.container.additive[x]	Base	example	hl7VS-additivePreservative	📦3.0.0	THO v7.2

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
mii-bb-1	error	Specimen.collection.bodySite	Bei der Angabe der Entnahmestelle muss ein ICD-O-3 Topographiecode oder ein SNOMED CT Code angegeben werden.	coding.where(system = 'http://snomed.info/sct' or system = 'http://terminology.hl7.org/CodeSystem/icd-o-3').exists()

Differential-Ansicht

Diese Struktur ist abgeleitet von MII_PR_Biobank_Specimen_Bioprobe_Core

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	MII_PR_Biobank_Specimen_Bioprobe_Core	Sample for analysis
Slices for extension				Content/Rules for all slices
extension:festgestellteDiagnose	S	0..1	Reference(Condition)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
extension:gehoertZu	S	0..1	Reference(MII PR Biobank Organization Sammlung Biobank)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
extension:anzahlAliquots	S	0..1	integer	MII EX Biobank Anzahl Aliquots URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
type
Slices for coding				Content/Rules for all slices
coding:miabis-type	S	0..1	Coding	Code defined by a terminology system Binding: DetailedSampleTypeVS (required)
system		0..1	uri	Identity of the terminology system Required Pattern: https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs
collection
method	S	0..1	CodeableConcept	Technique used to perform collection
coding	S	0..*	Coding	Code defined by a terminology system
system	S	1..1	uri	Identity of the terminology system
code	S	1..1	code	Symbol in syntax defined by the system
processing		0..*	BackboneElement
extension		1..*	Extension	Extension
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen		1..1	MII_EX_Biobank_Temperaturbedingungen	MII EX Biobank Temperaturbedingungen
extension:temperature-miabis	S	0..1	CodeableConcept	Sample storage temperature URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension Binding: Storage Temperature Value Set (required)
Slices for processing				Content/Rules for all slices
processing:lagerprozess		0..*	BackboneElement	Processing and processing step details
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen		1..1	MII_EX_Biobank_Temperaturbedingungen	MII EX Biobank Temperaturbedingungen
container		1..*	BackboneElement
type
coding	S	1..*	Coding	Code defined by a terminology system
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
Specimen.type.coding:miabis-type	Base	required	DetailedSampleTypeVS	📦1.3.0	MIABIS on FHIR Implementation Guide v1.3

Snapshot-AnsichtView

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Specimen		0..*	MII_PR_Biobank_Specimen_Bioprobe_Core	Sample for analysis
id	SΣ	0..1	id	Logical id of this artifact
meta	SΣ	0..1	Meta	Metadata about the resource
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
versionId	Σ	0..1	id	Version specific identifier
lastUpdated	Σ	0..1	instant	When the resource version last changed
source	SΣ	0..1	uri	Identifies where the resource comes from
profile	SΣ	0..*	canonical(StructureDefinition)	Profiles this resource claims to conform to
security	Σ	0..*	Coding	Security Labels applied to this resource Binding: All Security Labels (extensible): Security Labels from the Healthcare Privacy and Security Classification System.
tag	Σ	0..*	Coding	Tags applied to this resource Binding: CommonTags (example): Codes that represent various types of tags, commonly workflow-related; e.g. "Needs review by Dr. Jones".
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:feature		0..*	(Complex)	MII EX Biobank Feature R5 URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Specimen.feature
extension:probenebene	S	0..*	Coding	MII EX Biobank Ebene URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-ebene Binding: MII VS Biobank Probenebene (required)
extension:infektiositaetsstatus	S	0..1	CodeableConcept	MII EX Biobank Infektiositätsstatus URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-infektiositaetsstatus Binding: MII VS Biobank Biosafety-Level Einstufung [SNOMED CT] (required)
extension:focus	S	0..1	Reference(RelatedPerson | Group | Device | Substance | Location)	Specimen Focus URL: http://hl7.eu/fhir/laboratory/StructureDefinition/specimen-focus
extension:festgestellteDiagnose	S	0..1	Reference(Condition)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
extension:gehoertZu	S	0..1	Reference(MII PR Biobank Organization Sammlung Biobank)	URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
extension:anzahlAliquots	S	0..1	integer	MII EX Biobank Anzahl Aliquots URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	0..*	Identifier
accessionIdentifier	Σ	0..1	Identifier	Identifier assigned by the lab
status	?!SΣ	1..1	code	Binding: SpecimenStatus (required): Codes providing the status/availability of a specimen.
type	SΣ	1..1	CodeableConcept	Binding: hl7VS-specimenType (example): The type of the specimen.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Probenart SCT (extensible)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:miabis-type	SΣ	0..1	Coding	Code defined by a terminology system Binding: DetailedSampleTypeVS (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: https://fhir.bbmri-eric.eu/CodeSystem/miabis-detailed-samply-type-cs
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(Patient)
receivedTime	SΣ	0..1	dateTime	The time when specimen was received for processing
parent	S	0..*	Reference(Specimen)
request	S	0..*	Reference(ServiceRequest)
collection	S	1..1	BackboneElement
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:einstellungBlutversorgung	S	0..1	dateTime	MII EX Biobank Einstellung Blutversorgung URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/EinstellungBlutversorgung
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
collector	Σ	0..1	Reference(Practitioner | PractitionerRole)	Who collected the specimen
collected[x]	SΣ	1..1
collectedDateTime			dateTime
collectedPeriod			Period
duration	Σ	0..1	Duration	How long it took to collect specimen
quantity	S	0..1	SimpleQuantity(4.0.1)
id		0..1	string	Unique id for inter-element referencing
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
extension:pqTranslation		0..*	Quantity	Same quantity with different units URL: http://hl7.org/fhir/StructureDefinition/iso21090-PQ-translation
extension:quantityPrecision		0..1	integer	Explicit precision (number of significant decimal places) URL: http://hl7.org/fhir/StructureDefinition/quantity-precision
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
method	S	0..1	CodeableConcept	Technique used to perform collection Binding: FHIRSpecimenCollectionMethod (example): The technique that is used to perform the procedure.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	SΣ	0..*	Coding	Code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
bodySite	SC	0..1	CodeableConcept	Binding: SNOMEDCTBodyStructures (example): Codes describing anatomical locations. May include laterality. Constraints: mii-bb-1
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	Σ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:sct	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Biobank BodyStructures SCT (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:icd-o-3	SΣ	0..*	Coding	Code defined by a terminology system Binding: MII VS Onkologie ICD-O-3 Topographie (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://terminology.hl7.org/CodeSystem/icd-o-3
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
Slices for fastingStatus[x]	SΣ	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-relevantClincialInformation (extensible): Codes describing the fasting status of the patient.
fastingStatusCodeableConcept			CodeableConcept
fastingStatusDuration			Duration
fastingStatus[x]:fastingStatusCodeableConcept	Σ	0..1	CodeableConcept	Whether or how long patient abstained from food and/or drink Binding: hl7VS-relevantClincialInformation (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	Σ	0..*	Coding	Code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
Slices for processing	S	0..*	BackboneElement	Slice: Unordered, Open by value:$this.procedure
processing:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
Slices for extension		1..*	Extension	Extension Slice: Unordered, Open by value:url
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
extension:temperature-miabis	S	0..1	CodeableConcept	Sample storage temperature URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension Binding: Storage Temperature Value Set (required)
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
description		0..1	string	Textual description of procedure
procedure	S	1..1	CodeableConcept	Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	Σ	1..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:$this.system
coding:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:sct	SΣ	1..*	Coding	Code defined by a terminology system Binding: MII VS Biobank Laboratory Procedure SCT (preferred)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system Required Pattern: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
additive	S	0..*	Reference(MII PR Biobank Substance Additiv)
Slices for time[x]	S	0..1		Date and time of specimen processing Slice: Unordered, Open by type:$this
timeDateTime			dateTime
timePeriod			Period
time[x]:timePeriod	S	0..1	Period
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	0..1	dateTime	Starting time with inclusive boundary
end	SΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
processing:lagerprozess	S	0..*	BackboneElement	Processing and processing step details
id		0..1	string	Unique id for inter-element referencing
Slices for extension	S	1..*	Extension	Extension Slice: Unordered, Open by value:url
Slices for extension				Content/Rules for all slices
extension:temperaturbedingungen	S	1..1	Range	MII EX Biobank Temperaturbedingungen URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
description		0..1	string	Textual description of procedure
procedure		1..1	CodeableConcept	Indicates the treatment step applied to the specimen Binding: SpecimenProcessingProcedure (example): Type indicating the technique used to process the specimen. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: 1186936003
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
additive		0..*	Reference(Substance)	Material used in the processing step
Slices for time[x]		1..1	Period	Date and time of specimen processing Slice: Unordered, Closed by type:$this
Slices for time[x]				Content/Rules for all slices
time[x]:timePeriod		1..1	Period	Date and time of specimen processing
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	ΣC	1..1	dateTime	Starting time with inclusive boundary
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
container	S	1..*	BackboneElement
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
identifier	Σ	0..*	Identifier	Id for the container
description		0..1	string	Textual description of the container
type	S	1..1	CodeableConcept	Binding: MII VS Biobank Containertyp SCT (extensible)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
coding	SΣ	1..*	Coding	Code defined by a terminology system
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
capacity	S	0..1	SimpleQuantity(4.0.1)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
specimenQuantity	S	0..1	SimpleQuantity(4.0.1)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	1..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form Required Pattern: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
Slices for additive[x]	S	0..1		Slice: Unordered, Open by type:$this Binding: hl7VS-additivePreservative (example): Substance added to specimen container.
additiveCodeableConcept			CodeableConcept
additiveReference			Reference(Substance)
additive[x]:additiveReference		0..1	Reference(MII PR Biobank Substance Additiv)	Additive associated with container
condition	Σ	0..*	CodeableConcept	State of the specimen Binding: hl7VS-specimenCondition (extensible): Codes describing the state of the specimen.
note	S	0..*	Annotation
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Specimen.meta.security	Base	extensible	SecurityLabels	📍4.0.1	FHIR Std.
Specimen.meta.tag	Base	example	Common Tags	📍4.0.1	FHIR Std.
Specimen.language	Base	preferred	Common Languages	📍4.0.1	FHIR Std.
Specimen.status	Base	required	SpecimenStatus	📍4.0.1	FHIR Std.
Specimen.type	Base	example	hl7VS-specimenType	📦3.0.0	THO v7.2
Specimen.type.coding:sct	Base	extensible	MII VS Biobank Probenart SCT	📦2027.0.0-ballot	This IG
Specimen.type.coding:miabis-type	Base	required	DetailedSampleTypeVS	📦1.3.0	MIABIS on FHIR Implementation Guide v1.3
Specimen.collection.​method	Base	example	FHIR Specimen Collection Method	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite	Base	example	SNOMED CT Body Structures	📍4.0.1	FHIR Std.
Specimen.collection.​bodySite.coding:sct	Base	required	MII VS Biobank BodyStructures SCT	📦2027.0.0-ballot	This IG
Specimen.collection.​bodySite.coding:icd-o-3	Base	required	MII VS Onkologie ICD-O-3 Topographie	⏿2025.1.0	127.0.0.1
Specimen.collection.​fastingStatus[x]	Base	extensible	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.collection.​fastingStatus[x]:fastingStatusCodeableConcept	Base	required	hl7VS-relevantClincialInformation	📦3.0.0	THO v7.2
Specimen.processing.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.processing.​procedure.coding:sct	Base	preferred	MII VS Biobank Laboratory Procedure SCT	📦2027.0.0-ballot	This IG
Specimen.processing:lagerprozess.​procedure	Base	example	Specimen processing procedure	📍4.0.1	FHIR Std.
Specimen.container.type	Base	extensible	MII VS Biobank Containertyp SCT	📦2027.0.0-ballot	This IG
Specimen.container.additive[x]	Base	example	hl7VS-additivePreservative	📦3.0.0	THO v7.2
Specimen.condition	Base	extensible	hl7VS-specimenCondition	📦3.0.0	THO v7.2

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Specimen	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Specimen	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Specimen	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Specimen	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
mii-bb-1	error	Specimen.collection.bodySite	Bei der Angabe der Entnahmestelle muss ein ICD-O-3 Topographiecode oder ein SNOMED CT Code angegeben werden.	coding.where(system = 'http://snomed.info/sct' or system = 'http://terminology.hl7.org/CodeSystem/icd-o-3').exists()

Diese Struktur ist abgeleitet von MII_PR_Biobank_Specimen_Bioprobe_Core

Summary

Mandatory: 2 elements(5 nested mandatory elements)
Must-Support: 10 elements

Extensions

This structure refers to these extensions:

• https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose
• https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation
• https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/mii-ex-biobank-anzahl-aliquots
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-sample-storage-temperature-extension