MII IG Kerndatensatz-Modul Onkologie
2027.0.0-ballot.1 - Germany

This page is part of the MII IG Kerndatensatz-Modul Onkologie (v2027.0.0-ballot.1: Release) based on FHIR (HL7® FHIR® Standard) R4. This is the current published version in its permanent home (it will always be available at this URL). For a full list of available versions, see the Directory of published versions

ValueSet: MII VS Onkologie Marker-Gene HGNC

Offizielle URL: https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/ValueSet/mii-vs-onko-marker-gene-hgnc Version: 2027.0.0-ballot.1
Active Stand: 2026-09-15 Maschinenlesbarer Name: MII_VS_Onko_Marker_Gene_HGNC

Gensymbole der onkologisch gebraeuchlichen Marker-Gene aus der Genetik-Markerliste der §65c-Plattform, als HGNC-Gen-IDs. Auswahlunterstuetzung fuer Observation.component:gene-studied im Profil MII_PR_Onko_Genetische_Variante (extensible gebunden — weitere Gene sind zulaessig). Nicht-Gene der Quellliste (IHC-Marker, zytogenetische Aberrationen) sind bewusst ausgeschlossen; siehe die Kommentare in der FSH-Quelle und die IG-Seite zu den Variantentypen.

References

Logical Definition (CLD)

  • Include these codes as defined in http://www.genenames.org/geneId version ⏿20250704
    CodeDisplayDefinition
    HGNC:76ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase
    HGNC:427ALKALK receptor tyrosine kinase
    HGNC:1097BRAFB-Raf proto-oncogene, serine/threonine kinase
    HGNC:1100BRCA1BRCA1 DNA repair associated
    HGNC:1101BRCA2BRCA2 DNA repair associated
    HGNC:1133BTKBruton tyrosine kinase
    HGNC:2561CXCR4C-X-C motif chemokine receptor 4
    HGNC:3236EGFRepidermal growth factor receptor
    HGNC:3430ERBB2erb-b2 receptor tyrosine kinase 2
    HGNC:3689FGFR2fibroblast growth factor receptor 2
    HGNC:3765FLT3fms related receptor tyrosine kinase 3
    HGNC:5382IDH1isocitrate dehydrogenase (NADP(+)) 1
    HGNC:5383IDH2isocitrate dehydrogenase (NADP(+)) 2
    HGNC:6342KITKIT proto-oncogene, receptor tyrosine kinase
    HGNC:13726KMT2Clysine methyltransferase 2C
    HGNC:6407KRASKRAS proto-oncogene, GTPase
    HGNC:6470L1CAML1 cell adhesion molecule
    HGNC:6840MAP2K1mitogen-activated protein kinase kinase 1
    HGNC:7029METMET proto-oncogene, receptor tyrosine kinase
    HGNC:7059MGMTO-6-methylguanine-DNA methyltransferase
    HGNC:7562MYD88MYD88 innate immune signal transduction adaptor
    HGNC:7765NF1neurofibromin 1
    HGNC:7910NPM1nucleophosmin 1
    HGNC:7989NRASNRAS proto-oncogene, GTPase
    HGNC:7997NRG1neuregulin 1
    HGNC:8031NTRK1neurotrophic receptor tyrosine kinase 1
    HGNC:8032NTRK2neurotrophic receptor tyrosine kinase 2
    HGNC:8033NTRK3neurotrophic receptor tyrosine kinase 3
    HGNC:8803PDGFRAplatelet derived growth factor receptor alpha
    HGNC:8975PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
    HGNC:9177POLEDNA polymerase epsilon, catalytic subunit
    HGNC:9864RARAretinoic acid receptor alpha
    HGNC:9967RETret proto-oncogene
    HGNC:10261ROS1ROS proto-oncogene 1, receptor tyrosine kinase
    HGNC:10680SDHAsuccinate dehydrogenase complex flavoprotein subunit A
    HGNC:10681SDHBsuccinate dehydrogenase complex iron sulfur subunit B
    HGNC:10682SDHCsuccinate dehydrogenase complex subunit C
    HGNC:10683SDHDsuccinate dehydrogenase complex subunit D
    HGNC:25941TET2tet methylcytosine dioxygenase 2
    HGNC:11998TP53tumor protein p53

 

Expansion

Expansion performed internally based on codesystem HGNC Complete Set Gene Names v20250704 (CodeSystem)

This value set contains 40 concepts

SystemCodeDisplay (de)DefinitionJSONXML
http://www.genenames.org/geneId  HGNC:76ABL proto-oncogene 1, non-receptor tyrosine kinase
http://www.genenames.org/geneId  HGNC:427ALK receptor tyrosine kinase
http://www.genenames.org/geneId  HGNC:1097B-Raf proto-oncogene, serine/threonine kinase
http://www.genenames.org/geneId  HGNC:1100BRCA1 DNA repair associated
http://www.genenames.org/geneId  HGNC:1101BRCA2 DNA repair associated
http://www.genenames.org/geneId  HGNC:1133Bruton tyrosine kinase
http://www.genenames.org/geneId  HGNC:2561C-X-C motif chemokine receptor 4
http://www.genenames.org/geneId  HGNC:3236epidermal growth factor receptor
http://www.genenames.org/geneId  HGNC:3430erb-b2 receptor tyrosine kinase 2
http://www.genenames.org/geneId  HGNC:3689fibroblast growth factor receptor 2
http://www.genenames.org/geneId  HGNC:3765fms related receptor tyrosine kinase 3
http://www.genenames.org/geneId  HGNC:5382isocitrate dehydrogenase (NADP(+)) 1
http://www.genenames.org/geneId  HGNC:5383isocitrate dehydrogenase (NADP(+)) 2
http://www.genenames.org/geneId  HGNC:6342KIT proto-oncogene, receptor tyrosine kinase
http://www.genenames.org/geneId  HGNC:13726lysine methyltransferase 2C
http://www.genenames.org/geneId  HGNC:6407KRAS proto-oncogene, GTPase
http://www.genenames.org/geneId  HGNC:6470L1 cell adhesion molecule
http://www.genenames.org/geneId  HGNC:6840mitogen-activated protein kinase kinase 1
http://www.genenames.org/geneId  HGNC:7029MET proto-oncogene, receptor tyrosine kinase
http://www.genenames.org/geneId  HGNC:7059O-6-methylguanine-DNA methyltransferase
http://www.genenames.org/geneId  HGNC:7562MYD88 innate immune signal transduction adaptor
http://www.genenames.org/geneId  HGNC:7765neurofibromin 1
http://www.genenames.org/geneId  HGNC:7910nucleophosmin 1
http://www.genenames.org/geneId  HGNC:7989NRAS proto-oncogene, GTPase
http://www.genenames.org/geneId  HGNC:7997neuregulin 1
http://www.genenames.org/geneId  HGNC:8031neurotrophic receptor tyrosine kinase 1
http://www.genenames.org/geneId  HGNC:8032neurotrophic receptor tyrosine kinase 2
http://www.genenames.org/geneId  HGNC:8033neurotrophic receptor tyrosine kinase 3
http://www.genenames.org/geneId  HGNC:8803platelet derived growth factor receptor alpha
http://www.genenames.org/geneId  HGNC:8975phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
http://www.genenames.org/geneId  HGNC:9177DNA polymerase epsilon, catalytic subunit
http://www.genenames.org/geneId  HGNC:9864retinoic acid receptor alpha
http://www.genenames.org/geneId  HGNC:9967ret proto-oncogene
http://www.genenames.org/geneId  HGNC:10261ROS proto-oncogene 1, receptor tyrosine kinase
http://www.genenames.org/geneId  HGNC:10680succinate dehydrogenase complex flavoprotein subunit A
http://www.genenames.org/geneId  HGNC:10681succinate dehydrogenase complex iron sulfur subunit B
http://www.genenames.org/geneId  HGNC:10682succinate dehydrogenase complex subunit C
http://www.genenames.org/geneId  HGNC:10683succinate dehydrogenase complex subunit D
http://www.genenames.org/geneId  HGNC:25941tet methylcytosine dioxygenase 2
http://www.genenames.org/geneId  HGNC:11998tumor protein p53

Beschreibung der obigen Tabelle(n).