Dieses Profil beschreibt die konkreten Medikationen, die im Rahmen der systemischen Therapie für den oBDS dokumentiert werden.

Da im oBDS systemische und abwartende Therapie in einem Feld gruppiert sind, werden die Daten für die systemische und abwartende Therapie sowohl über eine FHIR-Prozedur (systemisch und abwartend) als auch als FHIR-Medikation abgedeckt.

Die Angaben zur systemischen onkologischen Medikation im oBDS werden mit den folgenden Datenpunkten abgebildet. Im Medikationsprofil der Systemischen Therapie sind das im Einzelnen:

• Start und Ende der Medikation
• Name des Behandlungsschemas
• Wirkstoffe (ATC-kodiert)

Konformität

Die vorliegende Profilierung ist kompatibel mit dem Prozedurenprofil der ISiK-Basismodule Stufe 4. https://simplifier.net/isik-medikation-v4/isikmedikationsinformation

Die vorliegende Profilierung ist derzeit nicht kompatibel mit dem EPA MedicationStatement, da dort unter MedicationStatement.medication explizit eine Referenz zu einer Medication-Ressource verlangt, während im vorliegenden Onkologie-MedicationStatement eine Kodierung über ATC präferiert wird. https://simplifier.net/epa-medication/epamedicationstatement

Mapping Datensatz zu FHIR

Die Zuordnung der Datensatzfelder ist im logischen Modell dokumentiert: MII LM Onkologie.

Mapping Einheitlicher onkologischer Basisdatensatz (oBDS) zu FHIR

Die oBDS-Mappings sind in der Artefaktdarstellung des Profils hinterlegt: MII PR Onkologie Systemische Therapie Medikation.

Beispiele

mii-exa-onko-systemische-therapie-medikation1

• Schlüsselelemente-Tabelle
• Differential-Tabelle
• Snapshot-Tabelle
• Statistiken/Referenzen
• Alle

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MII_PR_Medikation_MedicationStatement	Record of medication being taken by a patient
id	SΣ	0..1	id	Logical id of this artifact
meta	SΣ	0..1	Meta	Metadata about the resource
source	SΣ	0..1	uri	Identifies where the resource comes from
profile	SΣ	0..*	canonical(StructureDefinition)	Profiles this resource claims to conform to
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	0..*	Identifier	Identifikator
Slices for basedOn	SΣ	0..*	Reference(CarePlan | MedicationRequest)	Therapieplan oder Therapieempfehlung Slice: Unordered, Open by type:$this.resolve()
basedOn:tumorkonferenz	SΣ	0..1	Reference(MII PR Onkologie Tumorkonferenz)	Basiert auf
basedOn:therapieempfehlung	SΣ	0..1	Reference(MII PR Onkologie Therapieempfehlung Medikation)	Basiert auf
Slices for partOf	SΣ	1..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Teil von Slice: Unordered, Open by profile:resolve()
partOf:systemischeTherapie	SΣ	0..1	Reference(MII PR Onkologie Systemische Therapie)	Teil von
status	?!SΣ	1..1	code	Status Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
category	SΣ	0..1	CodeableConcept	Kategorie Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
Slices for coding	Σ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by pattern:$this
coding:usageCategory	Σ	0..*	Coding	Kategorie Anwendungsbereich Binding: Medication usage category codes (required) Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://terminology.hl7.org/CodeSystem/medication-statement-category
version		0..1	string	Version of the system - if relevant
code		0..1	code	Symbol in syntax defined by the system
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
coding:contextCode	Σ	0..1	Coding	Kategorie Kontext Binding: MII VS Medikation Fallkontext (required) Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://ihe-d.de/CodeSystems/FallkontextBeiDokumentenerstellung
version		0..1	string	Version of the system - if relevant
code		0..1	code	Symbol in syntax defined by the system
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
Slices for medication[x]	SΣ	1..1		Medikation Slice: Unordered, Closed by type:$this Binding: SNOMEDCTMedicationCodes (example): A coded concept identifying the substance or product being taken.
medicationCodeableConcept			CodeableConcept
medicationReference			Reference(Medication)
medication[x]:medicationReference	SΣ	0..1	Reference(MII PR Medikation Medication)	Referenz auf Medication (Alternative zur Inline-Codierung)
medication[x]:medicationCodeableConcept	SΣ	0..1	CodeableConcept	Medikation Code Binding: SNOMEDCTMedicationCodes (example): A coded concept identifying the substance or product being taken.
Slices for coding	SΣ	1..*	Coding	Wirkstoff der systemischen Medikation Slice: Unordered, Open by pattern:$this
coding:All Slices				Content/Rules for all slices
code	Σ	0..1	code	Symbol in syntax defined by the system
Slices for coding				Content/Rules for all slices
coding:Pharmazentralnummer	SΣ	0..*	Coding	PZN Code Required Pattern: At least the following
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://fhir.de/CodeSystem/ifa/pzn
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:atcClassDe	SΣ	0..*	Coding	ATC Klassifikation deutsche Version Binding: MII VS Medikation ATC (required) Required Pattern: At least the following
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://fhir.de/CodeSystem/bfarm/atc
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:atcClassEn	SΣ	0..*	Coding	Anatomical Therapeutic Chemical Classification System Required Pattern: At least the following
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://www.whocc.no/atc
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:UNII	SΣ	0..*	Coding	Unique Ingredient Identifier Binding: MII VS Onkologie Systemische Therapie Substanzen (UNII) (extensible) Required Pattern: At least the following
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://fdasis.nlm.nih.gov
code	SΣ	1..1	code	Symbol in syntax defined by the system
text	SΣ	0..1	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(Patient)	Who is/was taking the medication
context	SΣ	0..1	Reference(Encounter | EpisodeOfCare)	Kontext
Slices for effective[x]	SΣ	1..1		Zeitpunkt oder Zeitraum Slice: Unordered, Closed by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	SΣ	0..1	Period	Zeitraum
start	SΣC	0..1	dateTime	Startdatum der systemischen Medikation
end	SΣC	0..1	dateTime	Enddatum der systemischen Medikation
effective[x]:effectiveDateTime	SΣ	0..1	dateTime	Zeitpunkt
dateAsserted	SΣ	0..1	dateTime	Datum Bestätigung
informationSource	S	0..1	Reference(Patient | Practitioner | PractitionerRole | RelatedPerson | Organization)	Informationsquelle
reasonCode	S	0..*	CodeableConcept	Grund Code Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference	S	0..*	Reference(Condition | Observation | DiagnosticReport)	Grund Referenz
note	S	0..*	Annotation	Hinweis
text	SΣ	1..1	markdown	Protokoll
dosage	SC	0..*	DosageDE	Dosierung Constraints: dsg-1
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	SΣ	0..1	integer	The order of the dosage instructions
text	SΣ	0..1	string	Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'
timing	SΣ	0..1	TimingDE	Wann das Medikament verabreicht werden soll
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	SΣ	0..*	dateTime	When the event occurs
repeat	SΣC	0..1	Element	Wann das Ereignis stattfinden soll Constraints: tim-1, tim-2, tim-4, tim-5, tim-6, tim-7, tim-8, tim-9, tim-10, TimingSingleDosageForTimeOfDay, TimingSingleDosageForWhen, TimingBoundsUnitMatchesCode
Slices for bounds[x]	SΣ	0..1		Länge/Bereich der Längen oder (Start- und/oder End-)Grenzen Slice: Unordered, Closed by type:$this
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
bounds[x]:boundsDuration	SΣ	0..1	Duration	Dauer der Dosieranweisung ausgedrückt in UCUM-Einheiten
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	UCUM-Einheit für die Dauer Fixed Value: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
bounds[x]:boundsRange	SΣ	0..1	Range	Länge/Bereich der Längen oder (Start- und/oder End-)Grenzen
low	SΣ	0..1	SimpleQuantity(4.0.1)	Low limit
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
high	SΣ	0..1	SimpleQuantity(4.0.1)	High limit
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
bounds[x]:boundsPeriod	SΣ	0..1	Period	Länge/Bereich der Längen oder (Start- und/oder End-)Grenzen
start	SΣC	0..1	dateTime	Starting time with inclusive boundary
end	SΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
count	SΣ	0..1	positiveInt	Number of times to repeat
countMax	SΣ	0..1	positiveInt	Maximum number of times to repeat
duration	SΣ	0..1	decimal	How long when it happens
durationMax	SΣ	0..1	decimal	How long when it happens (Max)
durationUnit	SΣ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	SΣ	0..1	positiveInt	Ereignis tritt frequency-mal pro Zeitraum auf
frequencyMax	SΣ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	SΣ	0..1	decimal	Ereignis tritt frequency-mal pro Zeitraum auf
periodMax	SΣ	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	SΣ	0..1	code	s | min | h | d | wk | mo | a - Zeiteinheit (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	SΣ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	SΣ	0..*	time	Tageszeit für die Aktion
when	SΣ	0..*	code	Code für den Zeitraum des Auftretens Binding: EventTiming (required): Real world event relating to the schedule.
offset	SΣ	0..1	unsignedInt	Minutes from event (before or after)
Slices for asNeeded[x]	SΣ	0..1		Take "as needed" (for x) Slice: Unordered, Closed by type:$this Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
asNeeded[x]:asNeededBoolean	SΣ	0..1	boolean	Take "as needed" (for x)
asNeeded[x]:asNeededCodeableConcept	SΣ	0..1	CodeableConcept	Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
site	SΣ	0..1	CodeableConcept	Verabreichungsort Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
Slices for coding	SΣ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by pattern:$this
coding:SNOMED	SΣ	0..*	Coding	SNOMED CT Code Binding: Body Site - IPS (example): target site IPS Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
version		0..1	string	Version of the system - if relevant
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code	SΣ	1..1	code	Symbol in syntax defined by the system
route	SΣ	0..1	CodeableConcept	Verabreichungsweg Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
Slices for coding	SΣ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by pattern:$this
coding:EDQM	SΣ	0..1	Coding	EDQM Code Binding: Medicine EDQM Route of Administration - IPS (preferred): EDQM Standard Terms Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
version		0..1	string	Version of the system - if relevant
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://standardterms.edqm.eu
code	SΣ	1..1	code	Symbol in syntax defined by the system
coding:SNOMED	SΣ	0..1	Coding	SNOMED CT Code Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
version		0..1	string	Version of the system - if relevant
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
code	SΣ	1..1	code	Symbol in syntax defined by the system
doseAndRate	SΣ	0..*	Element	Menge des verabreichten Medikaments
Slices for dose[x]	SΣ	0..1		Amount of medication per dose Slice: Unordered, Closed by type:$this
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
dose[x]:doseQuantity	SΣ	0..1	SimpleQuantity	Menge des Medikaments pro Dosis Binding: Dosage DoseQuantity ValueSet (required)
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
dose[x]:doseRange	SΣ	0..1	Range	Amount of medication per dose
low	SΣ	0..1	SimpleQuantity(4.0.1)	Low limit
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
high	Σ	0..1	SimpleQuantity(4.0.1)	High limit
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
Slices for rate[x]	SΣ	0..1		Amount of medication per unit of time Slice: Unordered, Closed by type:$this
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
rate[x]:rateRatio	SΣ	0..1	Ratio	Amount of medication per unit of time
numerator	SΣ	0..1	Quantity	Numerator value
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
denominator	SΣ	0..1	Quantity	Denominator value
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
rate[x]:rateRange	SΣ	0..1	Range	Amount of medication per unit of time
low	SΣ	0..1	SimpleQuantity(4.0.1)	Low limit
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
high	SΣ	0..1	SimpleQuantity(4.0.1)	High limit
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
rate[x]:rateQuantity	SΣ	0..1	SimpleQuantity(4.0.1)	Amount of medication per unit of time
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
maxDosePerPeriod	SΣ	0..1	Ratio	Upper limit on medication per unit of time
numerator	SΣ	0..1	Quantity	Numerator value
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
denominator	SΣ	0..1	Quantity	Denominator value
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
maxDosePerAdministration	SΣ	0..1	SimpleQuantity(4.0.1)	Upper limit on medication per administration
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
MedicationStatement.​status	Base	required	Medication status codes	📍4.0.1	FHIR Std.
MedicationStatement.​category	Base	preferred	Medication usage category codes	📍4.0.1	FHIR Std.
MedicationStatement.​category.coding:usageCategory	Base	required	Medication usage category codes	📦4.0.1	FHIR Std.
MedicationStatement.​category.coding:contextCode	Base	required	MII VS Medikation Fallkontext	📦2027.0.0-ballot	MII IG Medikation v2027.0
MedicationStatement.​medication[x]	Base	example	SNOMED CT Medication Codes	📍4.0.1	FHIR Std.
MedicationStatement.​medication[x]:medicationCodeableConcept	Base	example	SNOMED CT Medication Codes	📍4.0.1	FHIR Std.
MedicationStatement.​medication[x]:medicationCodeableConcept.​coding:atcClassDe	Base	required	MII VS Medikation ATC	📦2027.0.0-ballot	MII IG Medikation v2027.0
MedicationStatement.​medication[x]:medicationCodeableConcept.​coding:UNII	Base	extensible	MII VS Onkologie Systemische Therapie Substanzen (UNII)	📦2027.0.0-ballot.1	This IG
MedicationStatement.​reasonCode	Base	example	Condition/Problem/Diagnosis Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​bounds[x]:boundsDuration.​comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​durationUnit	Base	required	UnitsOfTime	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​periodUnit	Base	required	UnitsOfTime	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​dayOfWeek	Base	required	DaysOfWeek	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​when	Base	required	EventTiming	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.asNeeded[x]	Base	example	SNOMED CT Medication As Needed Reason Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.asNeeded[x]:asNeededCodeableConcept	Base	example	SNOMED CT Medication As Needed Reason Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.site	Base	example	SNOMED CT Anatomical Structure for Administration Site Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.site.coding:SNOMED	Base	example	Body Site - IPS	📦2.0.1	International Patient Summary Implementation Guide v2.0
MedicationStatement.​dosage.route	Base	example	SNOMED CT Route Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.route.coding:EDQM	Base	preferred	Medicine EDQM Route of Administration - IPS	📦2.0.1	International Patient Summary Implementation Guide v2.0
MedicationStatement.​dosage.doseAndRate.dose[x]:doseQuantity	Base	required	Dosage DoseQuantity ValueSet	📦1.0.7	Medication IG DE v1.0
MedicationStatement.​dosage.doseAndRate.rate[x]:rateRatio.​numerator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.doseAndRate.rate[x]:rateRatio.​denominator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.maxDosePerPeriod.​numerator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.maxDosePerPeriod.​denominator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.

Constraints

Id	Grade	Path(s)	Description	Expression
TimingBoundsUnitMatchesCode	error	MedicationStatement.dosage.timing.repeat	boundsDuration.unit muss zur UCUM boundsDuration.code passen (z. B. 'Woche(n)' nur mit code='wk').	bounds.ofType(Duration).exists().not() or ( ( bounds.ofType(Duration).code = 'd' implies ( bounds.ofType(Duration).unit = 'Tag(e)' or bounds.ofType(Duration).unit = 'Tag' or bounds.ofType(Duration).unit = 'Tage' ) ) and ( bounds.ofType(Duration).code = 'wk' implies ( bounds.ofType(Duration).unit = 'Woche(n)' or bounds.ofType(Duration).unit = 'Woche' or bounds.ofType(Duration).unit = 'Wochen' ) ) and ( bounds.ofType(Duration).code = 'mo' implies ( bounds.ofType(Duration).unit = 'Monat(e)' or bounds.ofType(Duration).unit = 'Monat' or bounds.ofType(Duration).unit = 'Monate' ) ) and ( bounds.ofType(Duration).code = 'a' implies ( bounds.ofType(Duration).unit = 'Jahr(e)' or bounds.ofType(Duration).unit = 'Jahr' or bounds.ofType(Duration).unit = 'Jahre' ) ) )
TimingSingleDosageForTimeOfDay	error	MedicationStatement.dosage.timing.repeat	Wenn nur timeOfDay verwendet wird und täglich dosiert wird, ist die Angabe in einem einzigen Dosage-Element zu modellieren. Mehrere Dosage-Elemente sind nur zulässig, wenn sich die Dosis (Wert) unterscheidet.	( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).all( ( timing.repeat.dayOfWeek.empty() and timing.repeat.timeOfDay.exists() and timing.repeat.when.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ) implies ( ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.timeOfDay.exists() and timing.repeat.when.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).count() = 1 ) or ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.timeOfDay.exists() and timing.repeat.when.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).doseAndRate.dose.ofType(Quantity).value.distinct().count() > 1 ) ) )
TimingSingleDosageForWhen	error	MedicationStatement.dosage.timing.repeat	Wenn nur when verwendet wird und täglich dosiert wird, ist die Angabe in einem einzigen Dosage-Element zu modellieren. Mehrere Dosage-Elemente sind nur zulässig, wenn sich die Dosis (Wert) unterscheidet.	( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).all( ( timing.repeat.dayOfWeek.empty() and timing.repeat.when.exists() and timing.repeat.timeOfDay.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ) implies ( ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.when.exists() and timing.repeat.timeOfDay.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).count() = 1 ) or ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.when.exists() and timing.repeat.timeOfDay.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).doseAndRate.dose.ofType(Quantity).value.distinct().count() > 1 ) ) )
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management	text.`div`.exists()
dsg-1	error	MedicationStatement.dosage	If present, dosage must include free text or structured data	text.exists() or doseAndRate.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
tim-1	error	MedicationStatement.dosage.timing.repeat	if there's a duration, there needs to be duration units	duration.empty() or durationUnit.exists()
tim-2	error	MedicationStatement.dosage.timing.repeat	if there's a period, there needs to be period units	period.empty() or periodUnit.exists()
tim-4	error	MedicationStatement.dosage.timing.repeat	duration SHALL be a non-negative value	duration.exists() implies duration >= 0
tim-5	error	MedicationStatement.dosage.timing.repeat	period SHALL be a non-negative value	period.exists() implies period >= 0
tim-6	error	MedicationStatement.dosage.timing.repeat	If there's a periodMax, there must be a period	periodMax.empty() or period.exists()
tim-7	error	MedicationStatement.dosage.timing.repeat	If there's a durationMax, there must be a duration	durationMax.empty() or duration.exists()
tim-8	error	MedicationStatement.dosage.timing.repeat	If there's a countMax, there must be a count	countMax.empty() or count.exists()
tim-9	error	MedicationStatement.dosage.timing.repeat	If there's an offset, there must be a when (and not C, CM, CD, CV)	offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))
tim-10	error	MedicationStatement.dosage.timing.repeat	If there's a timeOfDay, there cannot be a when, or vice versa	timeOfDay.empty() or when.empty()

Diese Struktur ist abgeleitet von MII_PR_Medikation_MedicationStatement

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MII_PR_Medikation_MedicationStatement	Record of medication being taken by a patient
Slices for basedOn		0..*	Reference(CarePlan | MedicationRequest)	Therapieplan oder Therapieempfehlung Slice: Unordered, Open by type:$this.resolve()
basedOn:tumorkonferenz	S	0..1	Reference(MII PR Onkologie Tumorkonferenz)	Basiert auf
basedOn:therapieempfehlung	S	0..1	Reference(MII PR Onkologie Therapieempfehlung Medikation)	Basiert auf
Slices for partOf		1..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Teil von Slice: Unordered, Open by profile:resolve()
partOf:systemischeTherapie		0..1	Reference(MII PR Onkologie Systemische Therapie)	Teil von
Slices for medication[x]				Content/Rules for all slices
medication[x]:medicationReference		0..1	Reference(MII PR Medikation Medication)	Referenz auf Medication (Alternative zur Inline-Codierung)
medication[x]:medicationCodeableConcept		0..1	CodeableConcept	Medikation Code
coding		1..*	Coding	Wirkstoff der systemischen Medikation
code		0..1	code	Symbol in syntax defined by the system
Slices for coding				Content/Rules for all slices
coding:UNII		0..*	Coding	Unique Ingredient Identifier Binding: MII VS Onkologie Systemische Therapie Substanzen (UNII) (extensible)
subject		1..1	Reference(Patient)	Who is/was taking the medication
Slices for effective[x]				Content/Rules for all slices
effective[x]:effectivePeriod		0..1	Period	Zeitraum
start	S	0..1	dateTime	Startdatum der systemischen Medikation
end	S	0..1	dateTime	Enddatum der systemischen Medikation
note
text	S	1..1	markdown	Protokoll
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
MedicationStatement.​medication[x]:medicationCodeableConcept.​coding:UNII	Base	extensible	MII VS Onkologie Systemische Therapie Substanzen (UNII)	📦2027.0.0-ballot.1	This IG

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
MedicationStatement		0..*	MII_PR_Medikation_MedicationStatement	Record of medication being taken by a patient
id	SΣ	0..1	id	Logical id of this artifact
meta	SΣ	0..1	Meta	Metadata about the resource
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
versionId	Σ	0..1	id	Version specific identifier
lastUpdated	Σ	0..1	instant	When the resource version last changed
source	SΣ	0..1	uri	Identifies where the resource comes from
profile	SΣ	0..*	canonical(StructureDefinition)	Profiles this resource claims to conform to
security	Σ	0..*	Coding	Security Labels applied to this resource Binding: All Security Labels (extensible): Security Labels from the Healthcare Privacy and Security Classification System.
tag	Σ	0..*	Coding	Tags applied to this resource Binding: CommonTags (example): Codes that represent various types of tags, commonly workflow-related; e.g. "Needs review by Dr. Jones".
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	0..*	Identifier	Identifikator
Slices for basedOn	SΣ	0..*	Reference(CarePlan | MedicationRequest)	Therapieplan oder Therapieempfehlung Slice: Unordered, Open by type:$this.resolve()
basedOn:tumorkonferenz	SΣ	0..1	Reference(MII PR Onkologie Tumorkonferenz)	Basiert auf
basedOn:therapieempfehlung	SΣ	0..1	Reference(MII PR Onkologie Therapieempfehlung Medikation)	Basiert auf
Slices for partOf	SΣ	1..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Teil von Slice: Unordered, Open by profile:resolve()
partOf:systemischeTherapie	SΣ	0..1	Reference(MII PR Onkologie Systemische Therapie)	Teil von
status	?!SΣ	1..1	code	Status Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Reason for current status Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
category	SΣ	0..1	CodeableConcept	Kategorie Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	Σ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by pattern:$this
coding:usageCategory	Σ	0..*	Coding	Kategorie Anwendungsbereich Binding: Medication usage category codes (required) Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://terminology.hl7.org/CodeSystem/medication-statement-category
version		0..1	string	Version of the system - if relevant
code		0..1	code	Symbol in syntax defined by the system
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
coding:contextCode	Σ	0..1	Coding	Kategorie Kontext Binding: MII VS Medikation Fallkontext (required) Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: http://ihe-d.de/CodeSystems/FallkontextBeiDokumentenerstellung
version		0..1	string	Version of the system - if relevant
code		0..1	code	Symbol in syntax defined by the system
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
Slices for medication[x]	SΣ	1..1		Medikation Slice: Unordered, Closed by type:$this Binding: SNOMEDCTMedicationCodes (example): A coded concept identifying the substance or product being taken.
medicationCodeableConcept			CodeableConcept
medicationReference			Reference(Medication)
medication[x]:medicationReference	SΣ	0..1	Reference(MII PR Medikation Medication)	Referenz auf Medication (Alternative zur Inline-Codierung)
medication[x]:medicationCodeableConcept	SΣ	0..1	CodeableConcept	Medikation Code Binding: SNOMEDCTMedicationCodes (example): A coded concept identifying the substance or product being taken.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	SΣ	1..*	Coding	Wirkstoff der systemischen Medikation Slice: Unordered, Open by pattern:$this
coding:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	Σ	0..1	uri	Identity of the terminology system
version	Σ	0..1	string	Version of the system - if relevant
code	Σ	0..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
Slices for coding				Content/Rules for all slices
coding:Pharmazentralnummer	SΣ	0..*	Coding	PZN Code Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://fhir.de/CodeSystem/ifa/pzn
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:atcClassDe	SΣ	0..*	Coding	ATC Klassifikation deutsche Version Binding: MII VS Medikation ATC (required) Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://fhir.de/CodeSystem/bfarm/atc
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:atcClassEn	SΣ	0..*	Coding	Anatomical Therapeutic Chemical Classification System Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://www.whocc.no/atc
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:UNII	SΣ	0..*	Coding	Unique Ingredient Identifier Binding: MII VS Onkologie Systemische Therapie Substanzen (UNII) (extensible) Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://fdasis.nlm.nih.gov
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	SΣ	0..1	string	Plain text representation of the concept
subject	SΣ	1..1	Reference(Patient)	Who is/was taking the medication
context	SΣ	0..1	Reference(Encounter | EpisodeOfCare)	Kontext
Slices for effective[x]	SΣ	1..1		Zeitpunkt oder Zeitraum Slice: Unordered, Closed by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	SΣ	0..1	Period	Zeitraum
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	0..1	dateTime	Startdatum der systemischen Medikation
end	SΣC	0..1	dateTime	Enddatum der systemischen Medikation
effective[x]:effectiveDateTime	SΣ	0..1	dateTime	Zeitpunkt
dateAsserted	SΣ	0..1	dateTime	Datum Bestätigung
informationSource	S	0..1	Reference(Patient | Practitioner | PractitionerRole | RelatedPerson | Organization)	Informationsquelle
derivedFrom		0..*	Reference(Resource)	Additional supporting information
reasonCode	S	0..*	CodeableConcept	Grund Code Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference	S	0..*	Reference(Condition | Observation | DiagnosticReport)	Grund Referenz
note	S	0..*	Annotation	Hinweis
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
author[x]	Σ	0..1		Individual responsible for the annotation
authorReference			Reference(Practitioner | Patient | RelatedPerson | Organization)
authorString			string
time	Σ	0..1	dateTime	When the annotation was made
text	SΣ	1..1	markdown	Protokoll
dosage	SC	0..*	DosageDE	Dosierung Constraints: dsg-1
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	SΣ	0..1	integer	The order of the dosage instructions
text	SΣ	0..1	string	Freitext-Dosierungsanweisungen, z. B. 'Maximal 3x täglich 1 Stück bei Bedarf'
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	SΣ	0..1	TimingDE	Wann das Medikament verabreicht werden soll
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	SΣ	0..*	dateTime	When the event occurs
repeat	SΣC	0..1	Element	Wann das Ereignis stattfinden soll Constraints: tim-1, tim-2, tim-4, tim-5, tim-6, tim-7, tim-8, tim-9, tim-10, TimingSingleDosageForTimeOfDay, TimingSingleDosageForWhen, TimingBoundsUnitMatchesCode
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for bounds[x]	SΣ	0..1		Länge/Bereich der Längen oder (Start- und/oder End-)Grenzen Slice: Unordered, Closed by type:$this
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
bounds[x]:boundsDuration	SΣ	0..1	Duration	Dauer der Dosieranweisung ausgedrückt in UCUM-Einheiten
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	UCUM-Einheit für die Dauer Fixed Value: http://unitsofmeasure.org
code	SΣ	1..1	code	Coded form of the unit
bounds[x]:boundsRange	SΣ	0..1	Range	Länge/Bereich der Längen oder (Start- und/oder End-)Grenzen
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
low	SΣ	0..1	SimpleQuantity(4.0.1)	Low limit
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
high	SΣ	0..1	SimpleQuantity(4.0.1)	High limit
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
bounds[x]:boundsPeriod	SΣ	0..1	Period	Länge/Bereich der Längen oder (Start- und/oder End-)Grenzen
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	0..1	dateTime	Starting time with inclusive boundary
end	SΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
count	SΣ	0..1	positiveInt	Number of times to repeat
countMax	SΣ	0..1	positiveInt	Maximum number of times to repeat
duration	SΣ	0..1	decimal	How long when it happens
durationMax	SΣ	0..1	decimal	How long when it happens (Max)
durationUnit	SΣ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	SΣ	0..1	positiveInt	Ereignis tritt frequency-mal pro Zeitraum auf
frequencyMax	SΣ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	SΣ	0..1	decimal	Ereignis tritt frequency-mal pro Zeitraum auf
periodMax	SΣ	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	SΣ	0..1	code	s | min | h | d | wk | mo | a - Zeiteinheit (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	SΣ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	SΣ	0..*	time	Tageszeit für die Aktion
when	SΣ	0..*	code	Code für den Zeitraum des Auftretens Binding: EventTiming (required): Real world event relating to the schedule.
offset	SΣ	0..1	unsignedInt	Minutes from event (before or after)
code	Σ	0..1	CodeableConcept	BID | TID | QID | AM | PM | QD | QOD | + Binding: TimingAbbreviation (preferred): Code for a known / defined timing pattern.
Slices for asNeeded[x]	SΣ	0..1		Take "as needed" (for x) Slice: Unordered, Closed by type:$this Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
asNeeded[x]:asNeededBoolean	SΣ	0..1	boolean	Take "as needed" (for x)
asNeeded[x]:asNeededCodeableConcept	SΣ	0..1	CodeableConcept	Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
site	SΣ	0..1	CodeableConcept	Verabreichungsort Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	SΣ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by pattern:$this
coding:SNOMED	SΣ	0..*	Coding	SNOMED CT Code Binding: Body Site - IPS (example): target site IPS Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
route	SΣ	0..1	CodeableConcept	Verabreichungsweg Binding: SNOMEDCTRouteCodes (example): A coded concept describing the route or physiological path of administration of a therapeutic agent into or onto the body of a subject.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
Slices for coding	SΣ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by pattern:$this
coding:EDQM	SΣ	0..1	Coding	EDQM Code Binding: Medicine EDQM Route of Administration - IPS (preferred): EDQM Standard Terms Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://standardterms.edqm.eu
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
coding:SNOMED	SΣ	0..1	Coding	SNOMED CT Code Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
system	SΣ	1..1	uri	Identity of the terminology system Fixed Value: http://snomed.info/sct
version	Σ	0..1	string	Version of the system - if relevant
code	SΣ	1..1	code	Symbol in syntax defined by the system
display	Σ	0..1	string	Representation defined by the system
userSelected	Σ	0..1	boolean	If this coding was chosen directly by the user
text	Σ	0..1	string	Plain text representation of the concept
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	SΣ	0..*	Element	Menge des verabreichten Medikaments
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
Slices for dose[x]	SΣ	0..1		Amount of medication per dose Slice: Unordered, Closed by type:$this
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
dose[x]:doseQuantity	SΣ	0..1	SimpleQuantity	Menge des Medikaments pro Dosis Binding: Dosage DoseQuantity ValueSet (required)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
dose[x]:doseRange	SΣ	0..1	Range	Amount of medication per dose
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
low	SΣ	0..1	SimpleQuantity(4.0.1)	Low limit
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
high	Σ	0..1	SimpleQuantity(4.0.1)	High limit
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
Slices for rate[x]	SΣ	0..1		Amount of medication per unit of time Slice: Unordered, Closed by type:$this
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
rate[x]:rateRatio	SΣ	0..1	Ratio	Amount of medication per unit of time
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
numerator	SΣ	0..1	Quantity	Numerator value
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
denominator	SΣ	0..1	Quantity	Denominator value
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
rate[x]:rateRange	SΣ	0..1	Range	Amount of medication per unit of time
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
low	SΣ	0..1	SimpleQuantity(4.0.1)	Low limit
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
high	SΣ	0..1	SimpleQuantity(4.0.1)	High limit
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
rate[x]:rateQuantity	SΣ	0..1	SimpleQuantity(4.0.1)	Amount of medication per unit of time
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
maxDosePerPeriod	SΣ	0..1	Ratio	Upper limit on medication per unit of time
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
numerator	SΣ	0..1	Quantity	Numerator value
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
denominator	SΣ	0..1	Quantity	Denominator value
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
comparator	?!Σ	0..1	code	< | <= | >= | > - how to understand the value Binding: QuantityComparator (required): How the Quantity should be understood and represented.
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
maxDosePerAdministration	SΣ	0..1	SimpleQuantity(4.0.1)	Upper limit on medication per administration
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
value	SΣ	1..1	decimal	Numerical value (with implicit precision)
unit	SΣ	0..1	string	Unit representation
system	SΣC	1..1	uri	System that defines coded unit form
code	SΣ	1..1	code	Coded form of the unit
maxDosePerLifetime	Σ	0..1	SimpleQuantity(4.0.1)	Upper limit on medication per lifetime of the patient
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
MedicationStatement.​meta.security	Base	extensible	SecurityLabels	📍4.0.1	FHIR Std.
MedicationStatement.​meta.tag	Base	example	Common Tags	📍4.0.1	FHIR Std.
MedicationStatement.​language	Base	preferred	Common Languages	📍4.0.1	FHIR Std.
MedicationStatement.​status	Base	required	Medication status codes	📍4.0.1	FHIR Std.
MedicationStatement.​statusReason	Base	example	SNOMED CT Drug Therapy Status codes	📍4.0.1	FHIR Std.
MedicationStatement.​category	Base	preferred	Medication usage category codes	📍4.0.1	FHIR Std.
MedicationStatement.​category.coding:usageCategory	Base	required	Medication usage category codes	📦4.0.1	FHIR Std.
MedicationStatement.​category.coding:contextCode	Base	required	MII VS Medikation Fallkontext	📦2027.0.0-ballot	MII IG Medikation v2027.0
MedicationStatement.​medication[x]	Base	example	SNOMED CT Medication Codes	📍4.0.1	FHIR Std.
MedicationStatement.​medication[x]:medicationCodeableConcept	Base	example	SNOMED CT Medication Codes	📍4.0.1	FHIR Std.
MedicationStatement.​medication[x]:medicationCodeableConcept.​coding:atcClassDe	Base	required	MII VS Medikation ATC	📦2027.0.0-ballot	MII IG Medikation v2027.0
MedicationStatement.​medication[x]:medicationCodeableConcept.​coding:UNII	Base	extensible	MII VS Onkologie Systemische Therapie Substanzen (UNII)	📦2027.0.0-ballot.1	This IG
MedicationStatement.​reasonCode	Base	example	Condition/Problem/Diagnosis Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.additionalInstruction	Base	example	SNOMED CT Additional Dosage Instructions	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​bounds[x]:boundsDuration.​comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​durationUnit	Base	required	UnitsOfTime	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​periodUnit	Base	required	UnitsOfTime	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​dayOfWeek	Base	required	DaysOfWeek	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.repeat.​when	Base	required	EventTiming	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.timing.code	Base	preferred	TimingAbbreviation	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.asNeeded[x]	Base	example	SNOMED CT Medication As Needed Reason Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.asNeeded[x]:asNeededCodeableConcept	Base	example	SNOMED CT Medication As Needed Reason Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.site	Base	example	SNOMED CT Anatomical Structure for Administration Site Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.site.coding:SNOMED	Base	example	Body Site - IPS	📦2.0.1	International Patient Summary Implementation Guide v2.0
MedicationStatement.​dosage.route	Base	example	SNOMED CT Route Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.route.coding:EDQM	Base	preferred	Medicine EDQM Route of Administration - IPS	📦2.0.1	International Patient Summary Implementation Guide v2.0
MedicationStatement.​dosage.method	Base	example	SNOMED CT Administration Method Codes	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.doseAndRate.type	Base	example	DoseAndRateType	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.doseAndRate.dose[x]:doseQuantity	Base	required	Dosage DoseQuantity ValueSet	📦1.0.7	Medication IG DE v1.0
MedicationStatement.​dosage.doseAndRate.rate[x]:rateRatio.​numerator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.doseAndRate.rate[x]:rateRatio.​denominator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.maxDosePerPeriod.​numerator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.
MedicationStatement.​dosage.maxDosePerPeriod.​denominator.comparator	Base	required	QuantityComparator	📍4.0.1	FHIR Std.

Constraints

Id	Grade	Path(s)	Description	Expression
TimingBoundsUnitMatchesCode	error	MedicationStatement.dosage.timing.repeat	boundsDuration.unit muss zur UCUM boundsDuration.code passen (z. B. 'Woche(n)' nur mit code='wk').	bounds.ofType(Duration).exists().not() or ( ( bounds.ofType(Duration).code = 'd' implies ( bounds.ofType(Duration).unit = 'Tag(e)' or bounds.ofType(Duration).unit = 'Tag' or bounds.ofType(Duration).unit = 'Tage' ) ) and ( bounds.ofType(Duration).code = 'wk' implies ( bounds.ofType(Duration).unit = 'Woche(n)' or bounds.ofType(Duration).unit = 'Woche' or bounds.ofType(Duration).unit = 'Wochen' ) ) and ( bounds.ofType(Duration).code = 'mo' implies ( bounds.ofType(Duration).unit = 'Monat(e)' or bounds.ofType(Duration).unit = 'Monat' or bounds.ofType(Duration).unit = 'Monate' ) ) and ( bounds.ofType(Duration).code = 'a' implies ( bounds.ofType(Duration).unit = 'Jahr(e)' or bounds.ofType(Duration).unit = 'Jahr' or bounds.ofType(Duration).unit = 'Jahre' ) ) )
TimingSingleDosageForTimeOfDay	error	MedicationStatement.dosage.timing.repeat	Wenn nur timeOfDay verwendet wird und täglich dosiert wird, ist die Angabe in einem einzigen Dosage-Element zu modellieren. Mehrere Dosage-Elemente sind nur zulässig, wenn sich die Dosis (Wert) unterscheidet.	( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).all( ( timing.repeat.dayOfWeek.empty() and timing.repeat.timeOfDay.exists() and timing.repeat.when.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ) implies ( ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.timeOfDay.exists() and timing.repeat.when.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).count() = 1 ) or ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.timeOfDay.exists() and timing.repeat.when.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).doseAndRate.dose.ofType(Quantity).value.distinct().count() > 1 ) ) )
TimingSingleDosageForWhen	error	MedicationStatement.dosage.timing.repeat	Wenn nur when verwendet wird und täglich dosiert wird, ist die Angabe in einem einzigen Dosage-Element zu modellieren. Mehrere Dosage-Elemente sind nur zulässig, wenn sich die Dosis (Wert) unterscheidet.	( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).all( ( timing.repeat.dayOfWeek.empty() and timing.repeat.when.exists() and timing.repeat.timeOfDay.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ) implies ( ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.when.exists() and timing.repeat.timeOfDay.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).count() = 1 ) or ( ( %resource.ofType(MedicationRequest).dosageInstruction | %resource.ofType(MedicationDispense).dosageInstruction | %resource.ofType(MedicationStatement).dosage ).where( timing.repeat.dayOfWeek.empty() and timing.repeat.when.exists() and timing.repeat.timeOfDay.empty() and (timing.repeat.period.exists() and timing.repeat.period = 1) and (timing.repeat.periodUnit.exists() and timing.repeat.periodUnit = 'd') ).doseAndRate.dose.ofType(Quantity).value.distinct().count() > 1 ) ) )
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management	text.`div`.exists()
dsg-1	error	MedicationStatement.dosage	If present, dosage must include free text or structured data	text.exists() or doseAndRate.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
tim-1	error	MedicationStatement.dosage.timing.repeat	if there's a duration, there needs to be duration units	duration.empty() or durationUnit.exists()
tim-2	error	MedicationStatement.dosage.timing.repeat	if there's a period, there needs to be period units	period.empty() or periodUnit.exists()
tim-4	error	MedicationStatement.dosage.timing.repeat	duration SHALL be a non-negative value	duration.exists() implies duration >= 0
tim-5	error	MedicationStatement.dosage.timing.repeat	period SHALL be a non-negative value	period.exists() implies period >= 0
tim-6	error	MedicationStatement.dosage.timing.repeat	If there's a periodMax, there must be a period	periodMax.empty() or period.exists()
tim-7	error	MedicationStatement.dosage.timing.repeat	If there's a durationMax, there must be a duration	durationMax.empty() or duration.exists()
tim-8	error	MedicationStatement.dosage.timing.repeat	If there's a countMax, there must be a count	countMax.empty() or count.exists()
tim-9	error	MedicationStatement.dosage.timing.repeat	If there's an offset, there must be a when (and not C, CM, CD, CV)	offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))
tim-10	error	MedicationStatement.dosage.timing.repeat	If there's a timeOfDay, there cannot be a when, or vice versa	timeOfDay.empty() or when.empty()